Evidence map›Paper›PMID 40835817›Full record

Reviewnpj aging2025

Modulating biological aging with food-derived signals: a systems and precision nutrition perspective.

Carsten Carlberg, Andreas Blüthner, Irini Schoeman-Giziakis, Annemarie Oosting, Luca Cocolin

Abstract readReview
In one paragraph

Review in npj aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carsten CarlbergInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland. c.carlberg@pan.olsztyn.pl.
Andreas BlüthnerDr. Blüthner & Partner, Bad Dürkheim, Germany.
Irini Schoeman-GiziakisDanone Global Research and Innovation, Utrecht, The Netherlands.
Annemarie OostingCargill Food Solutions, Schipol, The Netherlands.
Luca CocolinDepartment of Agricultural, Forest and Food Sciences, University of Torino, Torino, Italy. lucasimone.cocolin@unito.it.

Funding

European Union's Horizon Europe research and innovation program 952601Polish National Science Centre 2023/49/B/NZ9/00402
6 · The paper itself

Abstract

Lifespan extension has not prevented age-related decline. We propose that diet acts as a molecular modulator of aging, influencing inflammation, the microbiome, and systemic resilience. Biological age markers and AI-powered multi-omics reveal actionable dietary targets, including food-derived signals and Nutrition Dark Matter. We highlight precision nutrition and the EIT Food Healthy Aging Think & Do Tank as pathways to align science, policy, and practice for healthy aging.

Identifiers

PMID40835817
PMCPMC12368197

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.