Evidence mapPaperPMID 40836841Full record

ReviewLab on a chip2025

Microfluidic technologies for wearable and implantable biomedical devices.

Ziheng Wang, Ankit Shah, Hyowon Lee, Chi Hwan Lee

Abstract readReview
In one paragraph

Review in Lab on a chip, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Packaging Glasses: From Containers to EncapsulationMaterials (Basel, Switzerland) · 2026
    Review
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ziheng WangSchool of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. lee2270@purdue.edu.
Ankit ShahWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. hwlee@purdue.edu.
Hyowon LeeWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. hwlee@purdue.edu.ORCID 0000-0001-7628-1441
Chi Hwan LeeSchool of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. lee2270@purdue.edu.ORCID 0000-0002-4868-7054

Funding

Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma careR01EY034901 · PURDUE UNIVERSITY · 2025 to 2025
$511k
National Science Foundation ECCS-1944480NEI NIH HHS R01 EY034901
6 · The paper itself

Abstract

Microfluidic technologies are transforming wearable and implantable biomedical devices by enabling precise, real-time analysis and control of biofluids at the microscale. Integrating soft, biocompatible materials with advanced sensing and fabrication techniques, these systems offer promising solutions for continuous health monitoring, targeted drug delivery, and responsive therapeutics. This review outlines critical design considerations, material strategies, and fluid handling mechanisms essential for device performance and biocompatibility. We systematically examine key fabrication approaches-including soft lithography, 3D printing, laser micromachining, and textile-based methods-highlighting their advantages and limitations for wearable and implantable applications. Representative use cases such as sweat analysis, interstitial fluid sampling, ocular diagnostics, wound monitoring, and

Indexed as

Lab-On-A-Chip DevicesMicrofluidic Analytical TechniquesProstheses and ImplantsWearable Electronic DevicesAnimalsHumans

Identifiers

PMID40836841
PMCPMC12368579

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.