Evidence map›Paper›PMID 40836924›Full record

ArticleiScience2025

Artificial intelligence diagnosis and heatmap agent for mitral valve prolapse using 3D cine echocardiography.

Defu Zhang, Miaoru Yu, Xueyuan Lin, Ying Guo, Xiaohua Liu, Qian Liu, Xiaofang Zhong, Yuanyuan Sheng, Shuyu Luo, Yuxiang Huang and 4 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Defu ZhangDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Miaoru YuDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Xueyuan LinDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Ying GuoDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Xiaohua LiuDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Qian LiuDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Xiaofang ZhongDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Yuanyuan ShengDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Shuyu LuoDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Yuxiang HuangDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Lixin ChenDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Jinfeng XuDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Xiaoxuan LinDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.
Yingying LiuDepartment of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection rate of mitral valve prolapse (MVP) has been increased by using 3D echocardiography. It would be clinically meaningful for accurate assessment of prolapse histology with advanced deep learning algorithms. However, recent studies mainly focus on automatic measurement and reconstruction of cardiac structures using voxel data, while seriously neglecting the automatic diagnosis and visualization using cine data. To address the gap, we propose an artificial intelligence agent to study diagnosis and heatmap for MVP. We include 481 cardiac cycles (8422 frames) from 151 subjects. Our agent achieves the AUC, accuracy and F1 of MVP diagnosis are 99.54%, 95.08%, and 94.12% in patient-levels. The Dice and Iou of heatmap of MVP are 70.35% and 56.39%, which is about 5% higher than that between senior and junior physicians. Our agent would provide standardizing diagnosis and intuitive visualization for the surgical management and treatment plans of MVP.

Indexed as

Biological sciencesComputer scienceHealth sciences

Identifiers

PMID40836924
PMCPMC12361798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.