ArticleiScience2025
Heterologous expression of heat-resistant obscure (Hero) proteins enhances thermotolerance in plants.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Biomolecular Condensates in Combined and Recurrent Plant Stresses: Integrating Phase Separation, Signal Prioritization, and Cross-Stress Memory.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improving plant stress tolerance and crop productivity is critical. Membraneless biomolecular condensates formed via liquid-liquid phase separation (LLPS) have been shown to mediate plant responses to various stresses, including heat. While recent advances have elucidated the LLPS role in stress tolerance mechanisms, translating these findings into practical strategies for enhancing plant resilience remains a formidable challenge. In this study, we investigated the effects of two human-derived RNA-binding proteins, Heat-resistant obscure 7 (Hero7) and Hero45, on abiotic stress tolerance in plants. When overexpressed heterologously, these proteins appear to enhance thermotolerance. Under heat stress, Hero7 and Hero45 undergo phase transitions consistent with LLPS, which correlates with the formation of larger processing bodies (PBs) and stress granules (SGs). This may contribute to the protection of mRNAs from heat-induced degradation, potentially improving heat resistance. The present findings demonstrate that LLPS modulation can enhance plant thermotolerance, offering a viable strategy for engineering stress-resistant crops.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.