Evidence map›Paper›PMID 40837735›Full record

ArticleLa matematica2025

Impact of Vascular Network Structure Heterogeneity on Retinal Tissue Oxygenation.

Julia Arciero, Brendan C Fry, Croix Gyurek, Amanda Albright, George Eckert, Gal Antman, Alice Verticchio, Brent Siesky, Alon Harris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in La matematica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia ArcieroDepartment of Mathematical Sciences, Indiana University Indianapolis, 402 N. Blackford St, LD 270, Indianapolis, IN 46202, USA.ORCID 0000-0002-2882-3653
Brendan C FryDepartment of Mathematics and Statistics, Metropolitan State University of Denver, Campus Box 38, P.O. Box 173362, Denver, CO 80217, USA.
Croix GyurekDepartment of Mathematical Sciences, Indiana University Indianapolis, 402 N. Blackford St, LD 270, Indianapolis, IN 46202, USA.
Amanda AlbrightDepartment of Mathematical Sciences, Indiana University Indianapolis, 402 N. Blackford St, LD 270, Indianapolis, IN 46202, USA.
George EckertDepartment of Biostatistics and Health Data Science, School of Medicine and Richard M. Fairbanks School of Public Health, Indiana University, 410 W. 10th St, Indianapolis, IN 46202, USA.
Gal AntmanDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, One Gustave L. Levy Place, Box 1183, New York, NY 10029, USA.
Alice VerticchioDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, One Gustave L. Levy Place, Box 1183, New York, NY 10029, USA.
Brent SieskyDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, One Gustave L. Levy Place, Box 1183, New York, NY 10029, USA.
Alon HarrisDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, One Gustave L. Levy Place, Box 1183, New York, NY 10029, USA.

Funding

Integration of clinical measures and theoretical modeling to quantify sectorial specific changes in ocular structure, function, and hemodynamicsR01EY030851 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARCIERO, JULIA, HARRIS, ALON · 2020 to 2023
$1.3M
SCH: SEEthroughGLAUCOMA: Smart Eye Emulator (SEE) to study glaucoma risk factorsR01EY034718 · NEI · UNIVERSITY OF MAINE ORONO · PI GUIDOBONI, GIOVANNA, HARRIS, ALON · 2022 to 2025
$975k
NEI NIH HHS R01 EY030851NEI NIH HHS R01 EY034718
6 · The paper itself

Abstract

A theoretical model of the human retina is simulated using two distinct vascular network geometries to predict the impact of heterogeneity in vascular network structure on retinal tissue oxygenation. Each vascular network is modeled as a combined heterogeneous representation of retinal arterioles and compartmental representation of capillaries, small venules, and large venules. A Green's function method is used to model oxygen transport in the arterioles, and a Krogh cylinder model is used in the capillaries and venules. Identical input arterial blood saturation (0.92), arteriolar pressure drop (16 mmHg), and arteriolar diameters by vessel order (

Indexed as

GlaucomaHeterogeneityMathematical modelOxygenationRetinaVascular network

Identifiers

PMID40837735
PMCPMC12360400

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.