ArticleWorld journal of gastrointestinal oncology2025
Different titration protocols in pain management after radical gastrectomy for gastric cancer patients.
Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Effectiveness of Non-Pharmacological Interventions on Postoperative Pain in Gastric Cancer: A Systematic Review and NMA Protocol.Journal of pain research · 2026Article
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5 authors.
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Abstract
backgroundEffective pain management after radical gastrectomy is crucial for patient recovery. With the promotion of enhanced recovery after surgery protocols, postoperative pain management has become a core component of perioperative care. However, controversy remains regarding the optimal frequency of analgesic titration for pain control.
aimTo compare the efficacy of 12-hour
methodsThis retrospective comparative study analyzed data from 120 patients who underwent radical gastrectomy between January 2021 and December 2022, with 52 patients receiving a 12-hour titration regimen and 68 patients receiving a 24-hour titration regimen. All patients received patient-controlled intravenous analgesia containing sufentanil and tropisetron postoperatively with identical initial settings.
resultsThe 12-hour titration group demonstrated significantly lower pain scores at 12 hours postoperatively compared to the 24-hour group (3.2
conclusionCompared to the 24-hour titration regimen, the 12-hour titration regimen provided more effective control of early postoperative pain after radical gastrectomy, reduced total analgesic consumption, lowered the incidence of related adverse reactions, improved patient satisfaction, and shortened hospital stays.
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