Evidence map›Paper›PMID 40837794›Full record

ReviewWorld journal of psychiatry2025

Interaction between the brain and multiple organ systems in schizophrenia.

Jin Lin, Si-Tong Feng, Zi-Yao Wu, Lin-Rui Dong, Dong-Qing Yin, Hong Zhu, Hong-Xiao Jia, Yan-Zhe Ning

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jin LinBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Si-Tong FengBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Zi-Yao WuBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Lin-Rui DongBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Dong-Qing YinBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Hong ZhuBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Hong-Xiao JiaBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Yan-Zhe NingBeijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is characterized by psychotic symptoms, negative symptoms, and cognitive deficits, profoundly affecting individuals and their families. The etiology is multifactorial, involving genetic, endocrine, and immunological risk factors. It is thought that schizophrenia is exclusively linked to alterations in brain structure and function, while the relationship between the brain and many organs may lack sufficient attention. Increasing evidence indicates abnormalities of the interactions between the brain and many organs in patients with schizophrenia. Inter-organ crosstalk affects the onset, course, and management of schizophrenia. Besides, the complex relationship between autonomic nervous system, endocrine system, and immune system further facilitates the development of schizophrenia. The present review summarizes the relationships between the brain and multiple organ systems in schizophrenia, providing new perspectives on the underlying pathophysiological mechanisms of schizophrenia.

Indexed as

Brain-body interactionsMultiple organic systemsPathophysiological mechanismsSchizophreniaSystemic integration

Identifiers

PMID40837794
PMCPMC12362655

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.