ArticleJournal of oral biology and craniofacial research
In-vitro evaluation of multicomponent scaffold with kappa carrageenan, tendon extracellular matrix and calcium-magnesium silicate for periodontal bone regeneration.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Development and characterisation of copper oxide nanoparticle-functionalized corn husk cellulose-PVA membranes for guided tissue regeneration.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chronic periodontitis is a complex combinatory disease that eventually upsets periodontal tissues, ultimately leading to tooth loss. In vertical bone loss defects, therapy includes surgical procedures, such as flap surgery with debridement associated with scaffolds, grafts, or membranes. The aim of the study is to fabricate a novel carrageenan, Calcium Magnesium Silicate (CaMgSiO), and ovine extracellular matrix (ECM)-based scaffold for periodontal bone regeneration. Materials and methods: To a 2 % carrageenan solution, 1 mg/mL of CaMgSiO and ECM was added. This homogenous solution was immersed in 0.15 M CaCl Result: Calcium was observed with a weight percentage of 16.7 %, silicate with 27.6 wt%, and magnesium with 2.8 wt% via EDS spectra. Kappa carrageenan, CaMgSiO + ECM scaffold has good agreement with red blood cells with a minimal lysis of 2 % at the concentration of 10 mg/mL, and the differentiation test showed maximum proliferation of cells. Conclusion: The novel CaMgSiO ECM scaffold significantly enhances cell proliferation; it is highly hemocompatible and has enhanced mineralization properties. Hence, incorporation of bioactive bioceramics induces stability as well as enhances the regeneration properties of the tendon-derived ECM.
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Registered trials
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