Evidence map›Paper›PMID 40838175›Full record

ArticleMediators of inflammation2025

Min-Soo Kim, Kang-In Lee, Heung Joo Yuk, Yousang Jo, Hyungjun Kim, Ki-Sun Park

Abstract read
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min-Soo KimKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Kang-In LeeKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Heung Joo YukKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Yousang JoKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Hyungjun KimKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Ki-Sun ParkKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.ORCID https://orcid.org/0000-0003-1322-767X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary dysmenorrhea (PD) is characterized by excessive uterine contraction and ischemic vasoconstriction, primarily driven by elevated levels of prostaglandins (PGs; PGF2α) and inflammatory mediators. Nonsteroidal antiinflammatory drugs (NSAIDs) remain the standard treatment for PD; however, their associated adverse effects necessitate the use of alternative therapeutic strategies.

Indexed as

Cyclooxygenase 2DysmenorrheaMyometriumNF-kappa BPlant ExtractsUterine ContractionAnimalsDisease Models, AnimalFemaleHumansMiceReactive Oxygen SpeciesSignal TransductionCyclooxygenase 2NF-kappa BPlant ExtractsReactive Oxygen SpeciesAster spathulifolius Maxim.NF-κB signalingoxidative stressprimary dysmenorrheauterine contraction

Identifiers

PMID40838175
PMCPMC12364593

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.