Evidence map›Paper›PMID 40838388›Full record

ArticleBiomacromolecules2025

Quantifying Chemically Modified Acetylation Induced Changes in the Plant Secondary Cell Wall Structure and Dynamics.

Murtaza Barkarar, Daipayan Sarkar, Christopher G Hunt, Josh V Vermaas

Abstract read
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Murtaza BarkararDepartment of Biochemistry and Molecular Biology, Michigan State University, 612 Wilson Road, East Lansing, Michigan 48824, United States.ORCID 0009-0000-1535-2576
Daipayan SarkarMSU-DOE Plant Research Laboratory, Michigan State University, 612 Wilson Road, East Lansing, Michigan 48824, United States.ORCID 0000-0002-4167-2108
Christopher G HuntForest Products Laboratory, USDA Forest Service, Madison, Wisconsin 53726, United States.ORCID 0000-0002-4799-7085
Josh V VermaasMSU-DOE Plant Research Laboratory, Michigan State University, 612 Wilson Road, East Lansing, Michigan 48824, United States.ORCID 0000-0003-3139-6469

Funding

Computational Exploration of Plant Natural Products Bioactivity and Bioavailability in Human HealthR35GM155317 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Joshua V. Vermaas · 2024 to 2026
$1.1M
NIGMS NIH HHS R35 GM155317
6 · The paper itself

Abstract

Wood that is resistant to fungal degradation is highly desirable, and chemical acetylation is one way to inhibit wood decay. The open question is whether acetylation inhibits decay strictly by reducing moisture content within the cell wall or if specific interactions with the acetyl group hinder motion within the cell wall and further inhibit decay. We investigate these hypotheses through molecular simulation, acetylating exposed hemicellulose and lignin hydroxyl groups in a secondary plant cell wall model. By comparing diffusion within the model, we find that acetyl group interactions alone do not account for reduced transport, with only modest changes in diffusion when water saturated acetylated cell walls expand at a constant water content. The most substantial changes in diffusion occur where the additional acetylation displaces water, decreasing the moisture content for the cell wall. These findings elucidate the molecular mechanism through which acetylation affects secondary plant cell walls at atomic resolution.

Indexed as

Cell WallPlantsAcetylationDiffusionLigninPolysaccharidesWaterWoodhemicelluloseLigninPolysaccharidesWater

Identifiers

PMID40838388
PMCPMC12421508

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.