Evidence map›Paper›PMID 40839384›Full record

ArticleJournal of the American Society of Nephrology : JASN2026

Enhanced Expression of the Female-Biased Gene Gsta2 in Male Proximal Tubule Cells Improves Renal Resilience to Ischemia-Reperfusion Injury.

Shun-Yang Cheng, Jinjin Guo, Taylor L Simonian, Paolo Caldarelli, Andrew P McMahon

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Targeting YAP1-Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Probing Molecular Mechanisms of Proximal Tubular Resilience and Repair.Journal of the American Society of Nephrology : JASN · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shun-Yang ChengDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0001-9718-0519
Jinjin GuoDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Taylor L SimonianDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0009-0004-7276-6918
Paolo CaldarelliDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California.ORCID 0000-0003-4455-7778
Andrew P McMahonDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0002-3779-1729

Funding

Single-cell analysis to promote kidney repairUC2DK126024 · NIDDK · WASHINGTON UNIVERSITY · PI HUMPHREYS, BENJAMIN D., KIM, JUNHYONG · 2020 to 2024
$3.7M
Sexual dimorphism in the mammalian kidneyR01DK126925 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 2020 to 2024
$2.6M
NIDDK NIH HHS 5R01DK126925-05NIDDK NIH HHS R01 DK126925NIDDK NIH HHS UC2 DK126024
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ischemia-reperfusionoxidative stressproximal tubule

Identifiers

PMID40839384
PMCPMC12890015

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.