Evidence map›Paper›PMID 40839411›Full record

ArticleChemPlusChem2025

Quantifying the Influence of Poly(Ethylene glycol) on the Micelle Formation of Nonionic Detergents.

Frank Müh, Julia Gätcke, Athina Zouni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemPlusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frank MühInstitute for Theoretical Physics, Johannes Kepler University Linz, Altenberger Strasse 69, 4040, Linz, Austria.ORCID https://orcid.org/0000-0002-8818-2616
Julia GätckeInstitute for Biology, Humboldt Universität zu Berlin, Leonor-Michaelis-Haus, Philippstrasse 13, 10095, Berlin, Germany.
Athina ZouniInstitute for Biology, Humboldt Universität zu Berlin, Leonor-Michaelis-Haus, Philippstrasse 13, 10095, Berlin, Germany.ORCID https://orcid.org/0000-0003-0561-6990

Funding

Collaborative Research Center TPA5German Research Foundation (DFG)TU Berlin EXC 2008/1-390540038
6 · The paper itself

Abstract

The influence of poly(ethylene glycol) (PEG with molecular weights between 400 and 4000) on the critical micelle concentration (CMC) of nonionic detergents with maltose as well as oligo(ethylene glycol) head groups is determined by using 8-anilinonaphthalene-1-sulfonate (ANS) as fluorescence probe. The CMC is found to increase with the concentration of PEG (0%-30% (w/v)) in a way that is determined by the molar concentration of oxyethylene (OE) units and independent of the molecular weight of the added polymer. The effect is explained with the extended conformation of PEG in aqueous solution allowing for an interaction of detergent monomers with individual OE units via their alkyl tails. The fluorescence spectra of ANS are found to exhibit two major emission peaks that are affected in position and intensity by binding to micelles as well as PEG. A model with two conformations of ANS combined with two binding sites in the micelles is used to explain the spectra and their correlation with detergent properties. The shapes of the titration curves are shown to depend on the aggregation number and the equilibrium constant describing binding of ANS to micelles and are analyzed to find that PEG competes with micelles for binding of ANS.

Indexed as

8‐anilinonaphthalene‐1‐sulfonatecharge–transfer statecritical micelle concentrationfluorescencepoly(ethylene glycol)

Identifiers

PMID40839411
PMCPMC12509515

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.