ArticleEnvironment international2025
Air pollution and cognitive performance in late life: the role of lipid profile - results from the Multi-Ethnic Study of Atherosclerosis (MESA).
Xi Pan, Robyn L McClelland, Lilah M Besser, Jana A Hirsch, Joel D Kaufman, Jing Cao, Timothy M Hughes
Abstract read
In one paragraphArticle in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Xi PanDepartment of Sociology, Texas State University, 601 University Drive, San Marcos 78666-4684 TX, USA. Electronic address: x_p5@txstate.edu.
Robyn L McClellandSchool of Public Health, University of Washington, Seattle, WA, USA. Electronic address: rmcclell@uw.edu.
Lilah M BesserComprehensive Center for Brain Health, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: lmb9767@miami.edu.
Jana A HirschUrban Health Collaborative, Epidemiology and Biostatistics, School of Public Health, Drexel University, Philadelphia, PA, USA. Electronic address: jah474@drexel.edu.
Joel D KaufmanEnvironmental & Occupational Health Sciences, University of Washington, Seattle, WA, USA. Electronic address: joelk@uw.edu.
Jing CaoPathology, Medical School, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: jing.cao2@utsouthwestern.edu.
Timothy M HughesGerontology and Geriatric Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC, USA. Electronic address: tmhughes@wakehealth.edu.
Funding
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)R01AG058969 · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2025 to 2025
$4.7MSUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · 1999 to 2001
$758kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · WAKE FOREST UNIVERSITY · 1999 to 2001
$616kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095160 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 1999 to 2001
$592kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095164 · NORTHWESTERN UNIVERSITY · 1999 to 2001
$511kSUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095168 · JOHNS HOPKINS UNIVERSITY · 1999 to 2000
$375kSUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · UNIVERSITY OF WASHINGTON · 1999 to 2005
$304kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · LA BIOMED RES INST/ HARBOR UCLA MED CTR · 1999 to 2001
$124kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY-ULTRASOUNDN01HC095167 · TUFTS MEDICAL CENTER · 1999 to 2001
$62kNCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NIA NIH HHS R01 AG054069NIA NIH HHS R01 AG058969
6 · The paper itselfAbstract
introductionEvidence on blood lipids in the air pollutant-cognition relationship is scarce. In this study, we identified the role of blood lipids in the air pollutant-cognition relationship in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort.
methodsThe study sample consisted of 1,518 adults who participated in MESA Exams 1-6 (2000-2018). Outcome were three composite scores of the Cognitive Abilities Screening Instrument (CASI) test, the Digit Symbol Coding test (DSC), and the Digit Span (DS) test at Exam 6. Outdoor residential concentrations of PM
resultsThe direct effect of NO DISCUSSION: TC and LDL-C were not mediators or clinically meaningful modifiers in the air pollutant-cognition relationship.
Indexed as
Air PollutantsAir PollutionCognitionEnvironmental ExposureLipidsAgedAged, 80 and overAtherosclerosisEthnicityFemaleHumansMaleMiddle AgedParticulate MatterAir PollutantsLipidsParticulate MatterAgingAir pollutionBlood lipidsCognitionDementia risks
Identifiers
PMID40840146
PMCPMC13258074
What Socratic holds
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LicenceCC BY-NC-ND
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