Evidence map›Paper›PMID 40840313›Full record

ReviewPlacenta2025

A call to standardize the nomenclature of human fetal membrane at the feto-maternal interface.

Claire E Kendal-Wright, John J Moore, Liping Feng, Ramkumar Menon, Anna L David, Tina T Chowdhury, Mia Frances Crowther, Connor Howe, Nanbert Zhong, Veronica Zaga Clavellina and 9 more

Abstract readReview
In one paragraph

Review in Placenta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Claire E Kendal-WrightDepartment of Obstetrics, Gynecology and Women's Health, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96826, USA.
John J MooreDepartments of Pediatrics and Reproductive Biology, Case Western Reserve University, Cleveland, OH, USA.
Liping FengDepartment of Obstetrics & Gynecology, Division of Reproductive Science, Duke University School of Medicine, Durham, NC, USA.
Ramkumar MenonDepartment of Obstetrics & Gynecology, Division of Basic Science and Translational Research, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Anna L DavidElizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK.
Tina T ChowdhuryCentre for Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK.
Mia Frances CrowtherCentre for Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK.
Connor HoweDepartment of Obstetrics, Gynecology and Women's Health, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96826, USA.
Nanbert ZhongInstitute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
Veronica Zaga ClavellinaDepartment of Immunobiochemistry, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Pilar Flores-EspinosaDepartment of Obstetrics & Gynecology, Division of Basic Science and Translational Research, The University of Texas Medical Branch at Galveston, Galveston, TX, USA; Department of Immunobiochemistry, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Nina TruongThe University of Texas Medical Branch John Sealy School of Medicine at Galveston, Galveston, TX, USA.
Vincent Sapin-DeourSchool of Medicine, Université Clermont Auvergne, Clermont-Ferrand, France.
Loïc BlanchonSchool of Medicine, Université Clermont Auvergne, Clermont-Ferrand, France.
Abir ZahraThe University of Texas Medical Branch John Sealy School of Medicine at Galveston, Galveston, TX, USA.
Ananth K KammalaDepartment of Obstetrics & Gynecology, Division of Basic Science and Translational Research, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Rahul CherukuriElectrical Engineering Department, Texas A&M University, College Station, TX, USA.
Lauren S RichardsonDepartment of Obstetrics & Gynecology, Division of Basic Science and Translational Research, The University of Texas Medical Branch at Galveston, Galveston, TX, USA. Electronic address: lestaffo@utmb.edu.
Fetal Membrane Society Consortium

Funding

Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M. · 2021 to 2025
$15.5M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
Autophagy and Intracellular Trafficking in Placental BiologyZIAES103370 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GUARDIA, CARLOS · 2022 to 2025
$9.2M
Paracrine control of the maternal-fetal interface critical for pregnancy wellnessR01HD110512 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI Sam Antonio MESIANO, JOHN J MOORE · 2023 to 2026
$2.3M
Developing trimester-specific placenta organ-on-chips to model healthy and oxidative stress and inflammation-associated pathologiesR01HD110400 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Lauren Stafford Richardson · 2023 to 2026
$2.3M
Developmental Reprogramming of Prostate Carcinogenesis by BPARC2ES018789 · NIEHS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HO, SHUK-MEI, MANCINI, MICHAEL A. · 2009 to 2010
$1.9M
Investigating the molecular mechanism of P-gp/NHERF-1 network at feto maternal interface and role of paracrine signaling of EVs containing drug transporter proteinsR01HD113193 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAMMALA, ANANTH KUMAR · 2023 to 2025
$914k
Intramural NIH HHS ZIA ES103370NICHD NIH HHS R01 HD110400NICHD NIH HHS R01 HD110512NICHD NIH HHS R01 HD113193NIEHS NIH HHS P30 ES030285NIEHS NIH HHS RC2 ES018789NIGMS NIH HHS U54 GM138062
6 · The paper itself

Abstract

Despite being one of the largest intrauterine tissues in surface area, the fetal membrane that lines the intrauterine cavity is often overlooked, forgotten, or misidentified in clinical and basic science research. The feto-maternal interface is comprised of the fetal membrane (fetal component) and decidua parietalis (maternal component), which lines the intrauterine cavity and provides essential mechanical, immune, hormonal, and transport support to maintain pregnancy. Fetal membrane plays an important role in triggering and regulating labor via complex signaling cascades. Whilst several researchers have investigated the membranes world-wide, nomenclature remains inconsistent, leading to widespread ambiguity across inter-disciplinary disciplines involving science, bioengineering, and reproductive medicine. The ongoing confusion regarding its terminology, origins, structure, and function has resulted in several significant issues, including diagnostic errors and misrepresentation clinically, limitations and inaccuracies in scientific research, and regulatory and clinical miscommunication. Therefore, the Fetal Membrane Society (FMS) calls upon the field to standardize fetal membrane nomenclature, define its architecture, and summarize its region-specific differences to facilitate understanding of its biological role. Clear and consistent identification of the fetal membrane is essential in improving research accuracy, clinical outcomes, and effective communication within and between the medical and scientific communities.

Indexed as

Extraembryonic MembranesMaternal-Fetal ExchangeTerminology as TopicFemaleHumansPregnancyAmniochorionic membraneAmnionChorioamniotic membraneChorionDeciduaExtracellular matrixGestational membraneNomenclature

Identifiers

PMID40840313
PMCPMC12993173

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.