Evidence mapPaperPMID 40842839Full record

SynthesisFrontiers in microbiology2025

Global research trends in gut microbiota and cellular senescence: a bibliometric and visual analysis from 2015 to 2025.

Shaoyang Huang, Jiangyan Li, Dandan Gu, Zhengliang Li, Hongyun Chen, Wei Xiong

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shaoyang Huang *College of Basic Medical Sciences, Dali University, Dali, China.
Jiangyan Li *College of Clinical Medicine, Dali University, Dali, China.
Dandan Gu *Department of Gastroenterology, Northeast Yunnan Regional Central Hospital, Zhaotong, China.
Zhengliang LiCollege of Clinical Medicine, Dali University, Dali, China.
Hongyun ChenCollege of Public Health, Dali University, Dali, China.
Wei XiongCollege of Basic Medical Sciences, Dali University, Dali, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The human body's intestinal microbiota is a vital "organ" that coexists with it and is intimately linked to both human health and illness. Human intestinal microbiota and its metabolites are a crucial component in the development of several diseases, according to an increasing number of studies that have started to examine the function of intestinal microbiota in various illnesses. Numerous recent studies have also shown a direct relationship between cellular senescence and the gut flora. The purpose of this study was to use bibliometric techniques to examine the themes and subjects of scholarly publications in this discipline during the past 10 or so years. Method: The Web of Science Core Collection (WOSCC) database was searched for material published between 2015 and 2025. The study used VOSviewer and Citespace to explore the characteristics of this literature. Specific analyzes covered the number of publications, countries/regions studied, research institutions, authors, journals, citations, and keyword hotspots. Results: This study analyzed 2,911 publications on research related to gut microbiota and cellular senescence between 2015 and 2025, with a rapid increase in annual publications from 2020 onwards, peaking in 2024 (492 publications), with the United States and China dominating in terms of publications, and the University of Groningen demonstrating excellent academic influence in this field, with Chen, Wei, De Vos, Paul and Zhang, Hao being the three most influential authors in this field, Nature is the most influential journal in its field with 5,857 total citations, "Oxidative stress," "Alzheimer's disease" and "immunotherapy" are current hot topics of research. Conclusion: Research in the field of gut microbiota and cellular aging is growing rapidly. Current research focuses on gut microbiota and disease mechanisms (e.g., Alzheimer's disease, immunotherapy, oxidative stress) and clinical translation, and interdisciplinary collaborations and technological innovations are expected to drive further development in this field. This bibliometric study provides a comprehensive analysis of the field and offers new ideas for future research.

Indexed as

bibliometric analysiscellular senescenceCiteSpacediseasegut microbiotaVOSviewer

Identifiers

PMID40842839
PMCPMC12364940

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.