Evidence map›Paper›PMID 40844090›Full record

ArticleEuropean journal of rheumatology2025

The Relationship Between the Monocyte-to-High-Density Lipoprotein-Cholesterol Ratio and Disease Activity in Patients with Psoriatic Arthritis.

Gizem Varkal, Ipek Türk, Ayşegül Yetişir, Özlem Doğan Ağbuga, Burak Mete, Süleyman Özbek

Abstract read
In one paragraph

Article in European journal of rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gizem VarkalDivision of Rheumatology, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0003-2270-102X
Ipek TürkDivision of Rheumatology, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0001-5192-9045
Ayşegül YetişirDivision of Rheumatology, Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0001-7070-3076
Özlem Doğan AğbugaDivision of Rheumatology, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0002-4998-9177
Burak MeteDivision of Public Health, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0002-0780-6176
Süleyman ÖzbekDivision of Rheumatology, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0002-8548-8126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this cross-sectional study was to analyze the monocyte-tohigh-density lipoprotein ratio (MHR) as an inflammatory marker in patients with psoriatic arthritis (PsA) and healthy controls (HCs), as well as to determine the association between MHR and PsA severity. Methods: This cross-sectional study included patients with PsA (n= 66) and age and sex-matched HCs (n= 68). Sociodemographic data and laboratory parameters were recorded in the study group. Disease Activity in PSoriatic Arthritis (DAPSA) was used to assess disease activity, while the Health Assessment Questionnaire (HAQ) was used for general health assessments. Disease Activity in PSoriatic Arthritis and HAQ were evaluated in the patient group. We compared sociodemographic, laboratory parameters, and the MHR between patients with PsA and HCs. Factors influencing MHR were assessed by regression analysis. Results: Patients with PsA revealed increased MHR compared to HCs (P= .025). In regression analysis, a DAPSA score of 15 or higher results in a 3.08 unit rise in the MHR, compared to a DAPSA score of 14 or below. In individuals with coronary artery disease (CAD), MHR increases by 7.56 units. Patients with moderate-severe PsA (DAPSA ≥ 15) had significantly elevated levels of C-reactive protein, erythrocyte sedimentation rate, and MHR compared to patients with remission-mild PsA (DAPSA ≤ 14) (P < .001, <.001, .026, respectively). Conclusions: Monocyte-to-high-density lipoprotein ratio can be used as an inflammatory marker in the follow-up of patients with PsA. Patients with PsA without evidence of active disease should also be evaluated for CAD in the presence of a high MHR value.

Identifiers

PMID40844090
PMCPMC12260450

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.