Evidence mapPaperPMID 40844669Full record

ReviewJournal of molecular histology2025

Ferroptosis: a novel pathway in the pathogenesis and treatment of endometriosis.

Xunshu Cheng, Muhammad Azhar Memon, Waseem Ali, Yonggang Ma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular histology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xunshu ChengSichuan University of Arts and Science, 635000, Dashon, People's Republic of China.
Muhammad Azhar MemonCollege of Veterinary Medicine, Yangzhsou University, Yangzhou, 225009, Jiangsu, People's Republic of China.
Waseem AliCollege of Veterinary Medicine, Yangzhsou University, Yangzhou, 225009, Jiangsu, People's Republic of China. 008301@yzu.edu.cn.
Yonggang MaCollege of Veterinary Medicine, Yangzhsou University, Yangzhou, 225009, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a common chronic disease, endometriosis (EMs) affects nearly 10% of women of childbearing age, may cause other complications such as infertility, and has a tendency to develop malignant tumors. Ferroptosis is a newly discovered apoptotic process characterized by intracellular free iron excess, which mediates Fenton reaction and eventually leads to lipid peroxidation in the cell membrane leading to cell death. The abnormal changes of intracellular iron concentration may lead to the accumulation of reactive oxygen species (ROS) and the imbalance of redox homeostasis, thus leading to the occurrence of iron death. At present, the pathogenesis and effect of iron death on EMs are not completely clear, and the study of its physiological and pathological mechanism is very important for its diagnosis and treatment. This article reviews the research progress of the occurrence and development of EMs in order to provide new ideas for the pathogenesis, diagnosis and treatment of EMs.

Indexed as

EndometriosisFerroptosisAnimalsFemaleHumansIronLipid PeroxidationReactive Oxygen SpeciesSignal TransductionIronReactive Oxygen SpeciesEndometriosisFerroptosisInfertilityIron overload

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.