Evidence mapPaperPMID 40844747Full record

ArticleJournal of endocrinological investigation2025

The overweight and obesity landscape in italy: data from the Italy cohort of the multi-country IMPACT-O study.

Dario Tuccinardi, Caterina Conte, Anastasia Lampropoulou, Marco Galasso, Laura Bertoccini, Mengyuan Shang, Esther Artime

Abstract readMulticenter Study
In one paragraph

Article in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dario Tuccinardi *Department of Endocrinology and Diabetes, University Campus Bio-Medico of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-9139-7159
Caterina Conte *San Raffaele Roma Open University, Rome, Italy.ORCID http://orcid.org/0000-0001-7066-5292
Anastasia LampropoulouEli Lilly and Company, Indianapolis, IN, USA.
Marco GalassoEli Lilly and Company, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0003-2655-4792
Laura BertocciniEli Lilly and Company, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0003-1883-2377
Mengyuan ShangIQVIA Ltd, London, UK.ORCID http://orcid.org/0000-0002-3283-120X
Esther ArtimeEli Lilly and Company, Indianapolis, IN, USA. artime_esther@lilly.com.ORCID http://orcid.org/0000-0003-4294-6462

Funding

Eli Lilly and Company Eli Lilly and Company
6 · The paper itself

Abstract

purposeThe IMPACT-O study was a multi-country, retrospective cohort study that utilized healthcare databases to describe the landscape/impact of obesity. Here, we describe the characteristics and management of adults with a first record of overweight/obesity or obesity in Italy between 2018 and 2022.

methodsThe IQVIA longitudinal patient database in Italy was used to identify individuals with a first record of overweight/obesity, as determined by diagnosis codes and/or body mass index (BMI) measurements (overweight/obesity cohort: BMI ≥ 25 kg/m

resultsThe overweight/obesity cohort included 38,144 individuals, and the obesity cohort 16,489 individuals. Most individuals with overweight/obesity (72.7%) and obesity (77.1%) presented with ≥ 1 ORCs. The most frequent ORCs among people with obesity were hypertension (48.0%), dyslipidemia (26.2%), osteoarthritis (23.9%), and type 2 diabetes (14.0%). The proportion of individuals receiving pharmacological therapies with an effect on weight was ≤ 1%; there were no records of lifestyle interventions or bariatric surgery.

conclusionsThis analysis suggests a high rate of ORCs in people with overweight or obesity at first available record, and limited use of pharmacological treatment with an effect on weight. This highlights the need for prompt recognition and formal diagnosis of overweight and obesity in healthcare settings, accompanied by early and intensive intervention. Patient management could be improved with a systematic and centralized recording of all interventions in this population.

Indexed as

ObesityOverweightAdultAgedBody Mass IndexCohort StudiesDatabases, FactualFemaleFollow-Up StudiesHumansItalyLife StyleMaleMiddle AgedRetrospective StudiesEpidemiologyObesityObesity-related complicationsOverweightReal-world data

Identifiers

PMID40844747
PMCPMC12640327

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.