Evidence map›Paper›PMID 40845003›Full record

ArticlePloS one2025

Unveiling the hidden burden of COVID-19 in Brazil's obstetric population with severe acute respiratory syndrome: A machine learning model.

Veridiana Freire Franco, Tatiana Assunção Zaccara, Ornella Scardua Ferreira, Rafaela Alkmin da Costa, Agatha Sacramento Rodrigues, Rossana Pulcinelli Francisco

Abstract read
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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Veridiana Freire FrancoDepartamento de Obstetricia e Ginecologia da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-2150-6612
Tatiana Assunção ZaccaraDivisão de Clínica Obstétrica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil.
Ornella Scardua FerreiraDepartamento de Estatistica da Universidade Federal do Espirito Santo, Vitoria, Espírito Santo, Brazil.
Rafaela Alkmin da CostaDepartamento de Obstetricia e Ginecologia da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.
Agatha Sacramento RodriguesDivisão de Clínica Obstétrica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil.
Rossana Pulcinelli FranciscoDepartamento de Obstetricia e Ginecologia da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.

Funding

Gates Foundation INV-027961
6 · The paper itself

Abstract

objectiveTo predict the actual number of COVID-19 cases in Brazilian pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome using a predictive model created based on data from Brazilian database.

methodsThis is a cross-sectional study with pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome (SARS) between January 2016 and November 2021 in Brazil. Patients were divided into two groups (COVID-19 and non-COVID-19) for comparative analysis, and a predictive model was constructed to classify cases without a defined causative agent.

main outcome measuresEstimated number of COVID cases in obstetric patients with SARS and no defined agent.

results38,774 pregnant and postpartum women diagnosed with SARS were identified and categorized by date and causative agent. Women in the COVID-19 group (19.138) were older (29.86 ± 7.20 years), self-reported more frequently as non-white race (50.9%), and more often had educational status marked as blank or ignored (29.6% and 26.9%, respectively) compared to the Other confirmed agents' group (2.233). The groups differed in all presented variables, and patients in the COVID-19 group were diagnosed more often in the third trimester of pregnancy or in the postpartum period. Using the XGBoost model, 13,978 cases of SARS with undefined etiology from 2020 and 2021 were reclassified: 13,799 (98.7%) as predicted COVID-19 and 179 (1.3%) as predicted non-COVID-19.

conclusionsThe number of COVID-19 cases and deaths in the obstetric population were even higher than reported by authorities, indicating a significant impact on the maternal mortality ratio during this period.

Indexed as

COVID-19Machine LearningPregnancy Complications, InfectiousSevere Acute Respiratory SyndromeAdultBrazilCross-Sectional StudiesFemaleHumansPostpartum PeriodPregnancySARS-CoV-2Young Adult

Identifiers

PMID40845003
PMCPMC12373234

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.