Evidence map›Paper›PMID 40845739›Full record

ArticleDomestic animal endocrinology2025

Differential responsiveness and signaling pathways for prostaglandin F2a on chemokine mRNA in bovine corpus luteum and luteinized granulosa cells.

Wenxiang Luo, Lisa B Wiltbank-Chau, Hemanta K Shrestha, Milo C Wiltbank

Abstract read
In one paragraph

Article in Domestic animal endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenxiang LuoDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706 USA; Department of Pediatrics, Division of Neonatology, University of Illinois at Chicago, Chicago, IL 60612 USA.
Lisa B Wiltbank-ChauDepartment of Microbiology, Weber State University, Ogden, Utah 84408 USA.
Hemanta K ShresthaDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706 USA.
Milo C WiltbankDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706 USA; Endocrinology-Reproductive Physiology Program, University of Wisconsin-Madison, Madison, Wisconsin 53706 USA. Electronic address: wiltbank@wisc.edu.

Funding

Defining the Mechanisms involved in LuteolysisR01HD050616 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI WILTBANK, MILO C · 2007 to 2010
$1.0M
NICHD NIH HHS R01 HD050616
6 · The paper itself

Abstract

Regulation of immune cells during luteolysis has been previously described, however inter- and intra-cellular pathways that mediate PGF

Indexed as

ChemokinesCorpus LuteumDinoprostGranulosa CellsRNA, MessengerSignal TransductionAnimalsCattleCells, CulturedFemaleGene Expression RegulationLuteolysisChemokinesDinoprostRNA, MessengerChemokineCorpus luteumGene expressionLuteinized granulosa cellLuteolysisMAPKNFkappaBPGF 2alphaPKC

Identifiers

PMID40845739
PMCPMC12452761

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.