Evidence map›Paper›PMID 40846556›Full record

ArticleInternational psychogeriatrics2026

Associations between depressive symptoms and subjective cognitive decline among diverse Hispanics/Latinos: Results from the study of Latinos-investigation of Neurocognitive Aging (SOL-INCA).

Lesley A Guareña, Alejandra Morlett-Paredes, Wassim Tarraf, Sayaka Kuwayama, Roberto González-Prado, Zvinka Z Zlatar, Ariana M Stickel, Krista M Perreira, Sylvia Wassertheil-Smoller, Donglin Zeng and 4 more

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Article in International psychogeriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Lesley A GuareñaDepartment of Psychology, University of Arizona, 1503 E. University Blvd., Building 68, Tucson, AZ 85721, United States.
Alejandra Morlett-ParedesDepartment of Neurosciences, University of California, 9500 Gilman Drive, La Jolla, CA 92093, United States.
Wassim TarrafInstitute of Gerontology and Department of Healthcare Services, Wayne State University, 87 East Ferry Street, Detroit, MI 48202, United States.
Sayaka KuwayamaDepartment of Neurosciences, University of California, 9500 Gilman Drive, La Jolla, CA 92093, United States.
Roberto González-PradoDepartment of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI 48202, United States.
Zvinka Z ZlatarDepartment of Psychiatry, University of California, 9500 Gilman Drive, La Jolla, CA 92093, United States.
Ariana M StickelDepartment of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI 48202, United States.
Krista M PerreiraUniversity of North Carolina, 103 South Building, CB #9100, Chapel Hill, NC 27599, United States.
Sylvia Wassertheil-SmollerAlbert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, United States.
Donglin ZengSchool of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, United States.
Linda C GalloDepartment of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI 48202, United States.
Martha L DaviglusCollege of Medicine, University of Illinois, 808 South Wood Street, Chicago, IL 60612, United States.
Carmen R IsasiAlbert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, United States.
Hector M GonzálezDepartment of Neurosciences, University of California, 9500 Gilman Drive, La Jolla, CA 92093, United States. Electronic address: hectorgonzalez@health.ucsd.edu.

Funding

Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseR01AG075758 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Charles DeCarli, Hector M Gonzalez · 2022 to 2026
$21.7M
Hispanic Community Health Study - NIDCDN01HC65235 · NHLBI · YESHIVA UNIVERSITY · PI KAPLAN, ROBERT · 2007 to 2012
$16.0M
OTHER FUNCTIONS - R&D - HISPANIC COMMUNITY HEALTH STUDYN01HC65233 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CAI, JAIWEN · 2007 to 2012
$15.1M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu · 2017 to 2026
$13.6M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65236 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DIVIGLUS, MARTHA · 2007 to 2012
$13.4M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65234 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI SCHNEIDERMAN, NEIL · 2007 to 2012
$13.1M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65237 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI TALAVERA, GREGORY · 2007 to 2013
$12.4M
Study of Latinos Investigation of Neurocognitive Aging 2R56AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2020 to 2021
$8.7M
Risk Factors for Alzheimer's Disease Among Latinos: Relationships Between Cardiovascular Disease Risk, Acculturation, Small Vessel Disease, and Alzheimer's BiomarkersK08AG075351 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ariana Stickel · 2022 to 2026
$770k
NHLBI NIH HHS HHSN268201000001INHLBI NIH HHS HHSN268201300003INHLBI NIH HHS N01HC65233NHLBI NIH HHS N01HC65234NHLBI NIH HHS N01HC65235NHLBI NIH HHS N01HC65236NHLBI NIH HHS N01HC65237NIA NIH HHS K08 AG075351NIA NIH HHS R01 AG075758NIA NIH HHS R56 AG048642NIEHS NIH HHS P30 ES027792NIH HHS HHSN268201300002INIH HHS HHSN268201300004INIH HHS HHSN268201300005I
6 · The paper itself

Abstract

introductionDepressive symptoms and subjective cognitive decline (SCD) are commonly reported prior to cognitive impairment. We examined associations between depressive symptoms and SCD among diverse Hispanic/Latino adults to better understand how depressive symptoms should be considered when interpreting SCD.

methodsThis cross-sectional study utilized data from Hispanic/Latino adults [n = 6189; Age: M= 63.4 years, SD= 8.2; 55 % female; 40.5 % reported more than high school education] from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

resultsHigher depressive symptoms were associated with worse global (β=0.37, SE=0.02) and domain-specific SCD (Memory: β=0.32, SE=0.02; Visual-Spatial Planning: β=0.27, SE=0.02; Executive Function: β=0.34, SE=0.02; ps < 0.001). These associations were significantly stronger for individuals with low cognitive status and current cognitive worry. DISCUSSION: These findings underscore the importance of assessing depressive symptoms in relation to SCD among diverse Hispanics/Latinos, especially among individuals with current cognitive worry and suspected cognitive impairment.

Indexed as

Cognitive DysfunctionDepressionHispanic or LatinoAgedCross-Sectional StudiesExecutive FunctionFemaleHumansMaleMiddle AgedNeuropsychological TestsWhiteCognitive statusCognitive worryDepressive symptomsHispanic/LatinoSubjective cognitive decline

Identifiers

PMID40846556
PMCPMC13001670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.