Evidence map›Paper›PMID 40846803›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Impact of motivational interviewing on psychosocial and symptom outcomes during breast cancer endocrine therapy.

Charlotte Ellis, Katherine Reeder-Hayes, Sarah Drier, Austin R Waters, Jennifer C Spencer, Stephanie Wheeler

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charlotte EllisDepartment of Health Policy and Management, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA. Charlottejellis2020@gmail.com.ORCID http://orcid.org/0000-0002-7134-7736
Katherine Reeder-HayesUniversity of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-6903-0177
Sarah DrierUniversity of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-6380-6285
Austin R WatersDepartment of Health Policy and Management, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-9947-8535
Jennifer C SpencerDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Stephanie WheelerDepartment of Health Policy and Management, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.

Funding

Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
Optimizing Endocrine Therapy Adherence through Motivational Interviewing and Text InterventionsR01CA237357 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI REEDER-HAYES, KATHERINE E, WHEELER, STEPHANIE BROOKE · 2019 to 2023
$3.0M
American Cancer Society MRSG-13-157-01-CPPBNCI NIH HHS R01 CA237357NCI NIH HHS T32 CA116339
6 · The paper itself

Abstract

purposeAdjuvant endocrine therapy (ET) is recommended to women with hormone receptor-positive (HR +) breast cancer for 5-10 years to reduce recurrence risk and mortality, but adhering to ET for this full period is challenging due to the physical and psychosocial effects of treatment. We sought to understand how participation in a patient-centered counseling intervention affected anxiety and depression, recurrence worry, and treatment related symptoms.

methodsWe conducted a single-arm pilot study over a 12-month period, consisting of five counselor-led motivational interviewing (MI) counseling sessions. Eligible participants were over 18 years old, English speaking, and had stage I-III HR + breast cancer. Survey data collected at baseline and 12 months assessed anxiety and depression, and cancer recurrence worry. Endocrine symptoms were assessed at the 12-month time point, reported descriptively, and age-stratified to examine if symptom burden and age were related.

resultsOf the 42 women who initiated the intervention, 35 completed the baseline and 12-month surveys. Most participants were over 50 (63%), non-Black and non-Hispanic (63%; 97%). Overall patient-reported anxiety and depression decreased from baseline to 12 months, though only the change in anxiety was statistically significant, while cancer worry increased slightly. The most reported endocrine symptoms were hot flashes, night sweats, vaginal dryness, disinterest in sex, and joint pain; endocrine symptoms did not vary by age.

conclusionThis study shows early promise in the efficacy of MI to improve anxiety, depression, recurrence worry, and treatment-related endocrine symptoms.

Indexed as

Antineoplastic Agents, HormonalBreast NeoplasmsMotivational InterviewingAdultAgedAnxietyChemotherapy, AdjuvantDepressionFemaleHumansMiddle AgedNeoplasm Recurrence, LocalPilot ProjectsAntineoplastic Agents, HormonalAdjuvant endocrine therapyBreast cancerMotivational interviewingPsychosocial symptomsRecurrence worry

Identifiers

PMID40846803
PMCPMC12373533

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.