Evidence mapPaperPMID 40846804Full record

Trial reportEuropean journal of clinical nutrition2025

Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes.

V Neuman, K Maratova, L Plachy, L Drnkova, S Pruhova, S Kolouskova, B Obermannova, S A Amaratunga, M Kulich, J Havlik and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

V NeumanDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia. Vit.Neuman@fnmotol.cz.ORCID 0000-0002-1745-5285
K MaratovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
L PlachyDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
L DrnkovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
S PruhovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
S KolouskovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
B ObermannovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
S A AmaratungaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
M KulichDepartment of Probability and Mathematical Statistics, Faculty of Mathematics and Physics, Charles University in Prague, Prague, Czechia.
J HavlikDepartment of Food Science, Czech University of Life Sciences, Prague, Czechia.
O CinekDepartment of Microbiology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Z SumnikDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.

Funding

Ministerstvo Zdravotnictví Ceské Republiky (Ministry of Health of the Czech Republic) AZV grant NU21-01-00085
6 · The paper itself

Abstract

aimsWe investigated whether a short period of tightly controlled low-carbohydrate diet (LCD) leads to a change in body weight, body composition, and muscle strength in children and young people with diabetes (CYPwD).

methodsThirty-five CYPwD were recruited into this randomized controlled cross-over study (20 female; age 14.5 ± 2.9 years). The interventions were five and five weeks of ready-made food box deliveries of isocaloric diets in random order: either LCD (94.5 ± 4.7 g/day) or recommended carbohydrate diet (RCD) (191 ± 19.2 g/day). The outcomes were body weight and body mass index (BMI) standard deviation scores (SDS), body fat percentage assessed by bioimpedance and muscle strength assessed by jumping mechanography at the end of each dietary intervention. The Welch two-sample t-tests were used to determine the difference in outcomes.

resultsAt the end of the LCD period, the participants had significantly lower body weight and BMI SDS than at the end of the RCD period (61.7 kg vs. 62.6 kg, P < 0.001, and 22.3 kg/m

conclusionsWe demonstrated that a short-term low-carbohydrate diet is able to decrease body weight, BMI, and decrease the percentage of body fat in CYPwD without negatively affecting their muscle function.

Indexed as

Adipose TissueBody WeightDiabetes Mellitus, Type 1Diet, Carbohydrate-RestrictedMuscle StrengthWeight LossAdolescentBody CompositionBody Mass IndexChildCross-Over StudiesFemaleHumansMale

Identifiers

PMID40846804
PMCPMC12580311

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.