ArticleBMC public health2025
Dietary acid load and its association with psychological disorders, sleep quality, and mood among Iranian older adults: a cross-sectional study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dietary acid load and oxidative stress in relation to sleep quality and duration among Iranian adults.Scientific reports · 2026Article
- Tea and coffee consumption in relation to depression and anxiety symptoms: findings from the multicentric LIPOKAP study.Scientific reports · 2026Article
- Unveiling the relationship between dietary patterns and sleep quality: cross-sectional evidence from university students in Jinan city.Frontiers in nutrition · 2026Article
- Food insecurity is associated with abdominal obesity, body roundness index, mental health, mood, and sleep-related outcomes among Iranian older adults.BMC public health · 2025Article
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5 authors.
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Abstract
objectiveThe rapid increase in the global elderly population poses significant mental health challenges. Dietary factors, particularly dietary acid load, are increasingly recognized as influential factors in mental health and psychological well-being. This study aims to elucidate the associations of dietary acid load with psychological disorders, sleep quality, and mood among Iranian Older Adults.
methodThis study included a randomly selected sample of 398 elderly individuals. Their dietary habits were examined using a validated food frequency questionnaire (FFQ). To estimate dietary acid load, three well-established indices were employed: potential renal acid load (PRAL), net endogenous acid production (NEAP), and dietary acid load (DAL). Mental health status was evaluated by applying the Iranian version of the Depression, Anxiety, and Stress Scale (DASS-21), which has been validated for accuracy. Furthermore, participants' sleep quality and mood were assessed through the Pittsburgh Sleep Quality Index (PSQI) and the Profile of Mood States (POMS), respectively.
resultIn fully adjusted models controlling for demographic, dietary, and lifestyle variables (e.g., age, BMI, socioeconomic status, caffeine intake), individuals in the highest tertile of the DAL index exhibited greater levels of stress than those in the lowest tertile (OR: 3.06, 95% CI = 1.43-6.57, p = 0.003). Elevated PRAL values were also linked to increased depressive symptoms (OR: 2.18, 95% CI = 1.04-4.58, p = 0.032). Higher levels of all three dietary acid load indices were significantly associated with poorer sleep quality (p < 0.05). However, no statistically significant associations were identified between dietary acid load and either anxiety or mood status (p > 0.05).
conclusionElderly individuals with elevated PRAL and DAL values showed increased symptoms of depression and stress, respectively. Additionally, higher dietary acid load was associated with poorer sleep quality. Prospective studies and clinical trials are needed to validate these relationships and to better understand the underlying mechanisms.
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