Evidence map›Paper›PMID 40847362›Full record

ArticleChinese medicine2025

Effects of acupuncture versus moxibustion on functional dyspepsia: a randomized clinical trial.

Yangke Mao, Pan Zhang, Zhaoxuan He, Yuke Teng, Zilei Tian, Sha Yang, Kuan Fang, Wei Zhang, Yuting Wang, Tao Yin and 1 more

Abstract read
In one paragraph

Article in Chinese medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yangke Mao *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Pan Zhang *Nervous System Disease Treatment Center, Traditional Chinese Medicine Hospital of Meishan, Meishan, 620032, Sichuan, China.
Zhaoxuan He *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Yuke TengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Zilei TianAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Sha YangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Kuan FangDepartment of Hospital Health Management/Physical Examination, Chengdu Fifth People's Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, 611130, China.
Wei ZhangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Yuting WangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Tao YinAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. yintao@cdutcm.edu.cn.
Fang ZengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. zengfang@cdutcm.edu.cn.

Funding

National Natural Science Foundation of China 81973960National Science Fund for Distinguished Young Scholars 82225050Natural Science Foundation of Sichuan Province 2023NSFSC1820
6 · The paper itself

Abstract

backgroundFunctional dyspepsia (FD) is a prevalent gastrointestinal disorder, despite its high prevalence and impact on quality of life, effective treatments are limited. Acupuncture and moxibustion, two complementary therapies based on traditional Chinese medicine, have shown potential in alleviating FD symptoms. However, the differences of acupuncture and moxibustion in FD are unclear.

methodsA total of 144 eligible FD patients were enrolled and randomly assigned to either the acupuncture or moxibustion group to receive 20 treatment sessions. The primary outcome was the Short-Form Leeds Dyspepsia Questionnaire (SFLDQ) total score after 4 weeks of treatment. Secondary outcomes included SFLDQ symptom-specific score, Nepean Dyspepsia Life Quality Index etc. Linear mixed-effects model was used for analyses.

resultsThere was no difference in SFLDQ total score after treatment with acupuncture compared with moxibustion (difference, 0.08[95% CI -0.634 to 0.794], p = 0.82), despite both groups were effective. However, the results of the secondary outcomes showed that compared with moxibustion, acupuncture was more effective in alleviating epigastric pain (difference, -0.318[95% CI -0.056 to -0.579], p = 0.017) and anxiety mood (difference, -2.893[95% CI -0.419 to -5.367], p = .022). On the other hand, moxibustion was more effective than acupuncture in reducing post-prandial fullness (difference, -0.3[95% CI -0.551 to -0.048], p = .02). The incidence of adverse events was similar between the groups.

conclusionsBoth the acupuncture and moxibustion groups showed significant improvement in FD symptoms. Although there were no significant differences between the groups at week 4 for the primary outcome, acupuncture exhibited greater improvement in addressing epigastric pain and reduction in anxiety symptoms while moxibustion demonstrated a larger reduction in improving post-prandial fullness. Choice of acupuncture and moxibustion should be tailored to the primary symptoms of FD patients to achieve optimal efficacy.

trial registrationChinese Clinical Trial Registry (ID: ChiCTR2100049496).

Indexed as

AcupunctureComplementary and alternative medicineEpigastric painFunctional dyspepsiaMoxibustionPost-prandial fullness

Identifiers

PMID40847362
PMCPMC12372385

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.