Evidence map›Paper›PMID 40847732›Full record

ReviewAdvanced healthcare materials2025

At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis.

Kaiwen Zhang, Chayla L Reeves, Mehrnoosh Moghaddar, Kate E Fox, Aaron Elbourne, Amy Gelmi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaiwen ZhangSchool of Science, RMIT University, Melbourne, 3000, Australia.
Chayla L ReevesSchool of Science, RMIT University, Melbourne, 3000, Australia.
Mehrnoosh MoghaddarSchool of Science, RMIT University, Melbourne, 3000, Australia.
Kate E FoxSchool of Engineering, RMIT University, Melbourne, 3000, Australia.
Aaron ElbourneSchool of Science, RMIT University, Melbourne, 3000, Australia.
Amy GelmiSchool of Science, RMIT University, Melbourne, 3000, Australia.ORCID 0000-0003-1636-6448

Funding

Australian Research Council DP200100612
6 · The paper itself

Abstract

Stem cell mechanosensitivity to their external environment is a key process in regulating and governing lineage commitment. The dynamic changes stem cells undergo due to mechanotransduction can reveal the processes triggering signaling pathways, however it is a highly complex methodology to capture these transient changes in living stem cells. Here, the use of new biophysical techniques to capture these changes in situ is discussed, namely emerging atomic force microscopy techniques, which are capable of high resolution and gentle biomechanical analysis.

Indexed as

BiophysicsMechanotransduction, CellularMicroscopy, Atomic ForceStem CellsAnimalsBiomechanical PhenomenaHumansatomic force microscopybiomaterialmechanobiologystem celltissue engineering

Identifiers

PMID40847732
PMCPMC12683222

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.