Evidence map›Paper›PMID 40850652›Full record

ArticleThe Journal of investigative dermatology2026

Endothelin-2 from Keratinocytes and its Association with Itch in Skin Diseases.

Yumeng Dong, Mrinal K Sarkar, Yuntian Wu, Xianying Xing, Matthew T Patrick, Bo Duan, Mehrnaz Gharaee-Kermani, Valerie Julia, Stephan Weidinger, J Michelle Kahlenberg and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yumeng DongDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA; Department of Dermatology, Xiangya third Hospital, Central South University, Changsha, China.
Mrinal K SarkarDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Yuntian WuDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Xianying XingDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Matthew T PatrickDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Bo DuanDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Mehrnaz Gharaee-KermaniDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Valerie JuliaGalderma, Lausanne, Switzerland.
Stephan WeidingerDepartment of Dermatology and Allergy, University Medical Center Schleswig-Holstein, Campus Kiel, Germany.
J Michelle KahlenbergDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Taubman Medical Research Institute, Michigan Medicine, Ann Arbor, Michigan, USA.
Johann E GudjonssonDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA; Taubman Medical Research Institute, Michigan Medicine, Ann Arbor, Michigan, USA; Mary H. Weiser Food Allergy Center, Michigan Medicine, Ann Arbor, Michigan, USA.
Lam C TsoiDepartment of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA; Mary H. Weiser Food Allergy Center, Michigan Medicine, Ann Arbor, Michigan, USA; Department of Computational Medicine & Bioinformatics, Michigan Medicine, Ann Arbor, Michigan, USA. Electronic address: alextsoi@med.umich.edu.

Funding

Immunogenomics and Systems Biology CoreUC2AR081033 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Johann Eli Gudjonsson, Lam Cheung Tsoi · 2022 to 2026
$3.3M
Integrative and trans-ethnic study to understand psoriasis associated signalsR01AR080662 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lam Cheung Tsoi · 2023 to 2026
$1.4M
NIAMS NIH HHS R01 AR080662NIAMS NIH HHS UC2 AR081033
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ET-2IL-31ItchKeratinocytesPrurigo nodularis

Identifiers

PMID40850652
PMCPMC13289584

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.