Evidence map›Paper›PMID 40850989›Full record

ArticleCurrent microbiology2025

Biological Activities of Aspergillus niger MF6: Antimicrobial, Antioxidant, and Cytotoxic Potential of Marine-Derived Fungus Metabolites.

Moaz M Hamed, Mohamed A A Abdrabo, Lamis Sh Abdelfattah, Yasser A Geneid

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Moaz M HamedNational Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt. Moaz-micro@hotmail.com.ORCID http://orcid.org/0000-0002-2608-085X
Mohamed A A AbdraboNational Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt.
Lamis Sh AbdelfattahNational Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt.
Yasser A GeneidNational Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt.

Funding

National Institute of Oceanography and Fisheries MP/3401
6 · The paper itself

Abstract

Marine-derived fungi have emerged as a promising source of bioactive compounds with therapeutic potential. This study investigates the biological activities of Aspergillus niger MF6, a fungal isolate derived from coral reefs along the Hurghada coast in the Red Sea, Egypt. The isolate demonstrated significant antimicrobial activity, with broad-spectrum inhibition against pathogens, including E. coli, S. aureus, and C. albicans, achieving inhibition zones up to 20 mm. Ethyl acetate was identified as the most effective solvent for extracting bioactive compounds, facilitating the isolation of metabolites responsible for antimicrobial activity. Antioxidant assays revealed robust activity, with dose-dependent scavenging effects across multiple mechanisms. Furthermore, cytotoxicity assays against HepG-2 and MCF-7 cancer cell lines demonstrated moderate cytotoxic activity, with IC

Indexed as

Anti-Infective AgentsAntineoplastic AgentsAntioxidantsAspergillus nigerAnimalsAnthozoaAquatic OrganismsCandida albicansCell Line, TumorEgyptEscherichia coliGas Chromatography-Mass SpectrometryHumansIndian OceanMCF-7 CellsMicrobial Sensitivity TestsAnti-Infective AgentsAntineoplastic AgentsAntioxidants

Identifiers

PMID40850989

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.