Evidence map›Paper›PMID 40851242›Full record

ReviewRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Physical exercise and irisin: managing obesity and related comorbidities.

Cristina Elena Negroiu, Robertina Iulia Tudoraşcu, Suzana Dănoiu, Vlad Pădureanu, Sânziana Godeanu, Raluca Dănoiu, Adrian Ionuţ Ungureanu, Maria Cristina Beznă, Cristiana Gianina Moise

Abstract readReview
In one paragraph

Review in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristina Elena NegroiuDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, Romania; irtudorascu@gmail.com; cristina.negroiu@yahoo.ro.
Robertina Iulia Tudoraşcu
Suzana Dănoiu
Vlad Pădureanu
Sânziana Godeanu
Raluca Dănoiu
Adrian Ionuţ Ungureanu
Maria Cristina Beznă
Cristiana Gianina Moise

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We live in an obesity pandemic characterized by sedentary lifestyles and unhealthy eating habits among more and more people. Therefore, it is crucial to understand the pathophysiology of obesity. A myokine secreted during exercise, irisin, has been the subject of many studies in recent years. It is well-known that physical exercise is one of the key therapeutic pillars in the fight against obesity. Irisin is a polypeptide hormone released during physical activity, and once it enters the bloodstream, it has numerous effects on the human body. This review aimed to highlight the latest studies on irisin, focusing on its structure, the mechanisms behind its release into the bloodstream, its effects on various organs, and, last but not least, how its serum levels change in different pathologies and its therapeutic effects.

Indexed as

ExerciseFibronectinsObesityComorbidityHumansFibronectinsFNDC5 protein, humanbrown adipose tissueirisinobesityphysical exercise

Identifiers

PMID40851242
PMCPMC12509513

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.