SynthesisFrontiers in nutrition2025
Effects of protein supplementation on body composition, physiological adaptations, and performance during endurance training: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Beyond the bare minimum: the case for revised physical activity guidelines and protein intake recommendations that maximise healthspan.Frontiers in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study aimed to evaluate the long-term effects of endurance training combined with protein supplementation on body composition, physiological adaptations (aerobic/anaerobic capacity), and performance. Methods: A systematic search was conducted in Web of Science, PubMed, and SPORTDiscus databases on April 16, 2025, using the keywords "endurance training" and "protein supplementation." Meta-analysis was conducted using a random-effects model, and the main effect size of each outcome was summarized using the standard mean difference (SMD), and moderators were explored using subgroup and regression analyses. Results: A total of 23 randomized cross-over trials involving 1,146 participants were included. The results showed that protein supplementation during endurance training led to a small, nonsignificant increase in lean body mass (SMD = 0.13, 95% CI: -0.01, 0.28; Discussion: In summary, protein supplementation during endurance training appears to modestly enhance endurance performance (TTE) and may offer small benefits for lean body mass, particularly in untrained individuals. However, it does not significantly affect overall body weight, fat mass, or aerobic/anaerobic capacity in the general population. Systematic review registration: Identifier, CRD420251034453, https://www.crd.york.ac.uk/PROSPERO/recorddashboard.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.