ArticleFrontiers in nutrition2025
Predictive value of composite nutritional indicators geriatric nutritional risk index and controlling nutritional status for mortality risk in early-onset cancer survivors.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Performance comparison of a neuro-symbolic large language model system versus conventional AI models and human experts in cholangitis management.BMC medical informatics and decision making · 2026Article
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6 authors.
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Abstract
Background: Malnutrition represents a critical determinant of adverse clinical outcomes and substantial disease burden in cancer patients. Despite the established prognostic value of Geriatric Nutritional Risk Index (GNRI) and Controlling Nutritional Status (CONUT) as composite inflammation-immune-nutrition indices in elderly cancer patients, their utility in early-onset (EO) cancer survivors remains unclear. Methods: This retrospective study evaluated GNRI and CONUT for predicting mortality in 3,273 early-onset (EO) cancer survivors, with a development cohort ( Results: In the development cohort, GNRI < 98 and CONUT ≥ 2 independently predicted elevated risks of all-cause mortality (HR = 3.36, 95%CI = 2.69-4.19, Conclusion: This study is the first to validate GNRI and CONUT as effective composite inflammation-immune-nutrition indices for identifying high-risk EO cancer survivors. Composite stratification combining both indices enhances multidimensional inflammation-immune-nutrition risk assessment, offering a practical framework for prognostication and personalized care in this population.
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