ReviewAnnals of medicine and surgery (2012)2025
Effects of preoperative carbohydrate loading on postoperative outcomes in patients undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The effect of perioperative oral carbohydrate loading on postoperative outcomes in patients undergoing orthopedic surgeries: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cholecystectomy is one of the most common procedures performed across the world. With efforts to maximize good postoperative status, one such technique involves preoperative carbohydrate loading. Methods: A thorough literature search was performed across three databases to identify articles published up to August 2024. The screening was conducted to select all primary studies evaluating the role of preoperative carbohydrate loading in patients undergoing laparoscopic cholecystectomy. Statistical analysis was conducted via RevMan using a random-effects model. Results: Thirteen records were included for quantitative synthesis, encompassing 827 participants (415 in the carbohydrate arm and 412 in the fasting arm). Carbohydrate loading was associated with significantly higher insulin levels compared to the control group (standard mean deviation [SMD]: -0.60; 95% confidence interval [CI]: -0.87, -0.34; Conclusion: Our analysis suggests that preoperative carbohydrate loading is linked with reduced postoperative pain, incidence of nausea, and superior insulin parameters. Further research is needed to strengthen these findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.