Evidence map›Paper›PMID 40852355›Full record

ReviewFrontiers in medicine2025

Rsearch progress on the relationship between aging and microbiota in sarcopenia.

Jing-Ping Cheng, Xiang Chen, Jia-Xin Chen

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jing-Ping Cheng *Department of Gerontology, CR & WISCO General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, China.
Xiang Chen *School of Medicine, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Jia-Xin ChenDepartment of Gerontology, CR & WISCO General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is an age-related skeletal muscle disease associated with adverse outcomes such as falls, decreased function, frailty, and death, and is a significant global public health problem that impairs the functioning of individuals. Aging is intensifying, the number of people with sarcopenia is increasing, and there are currently no specific treatment drugs for sarcopenia. The clinical pathogenesis of sarcopenia is extremely complex, and the underlying mechanism of immunosenescence and dysbiosis associated with aging on sarcopenia is not well studied, and they are also potential therapeutic targets for sarcopenia. This review mainly discusses the relationship between sarcopenia from the perspective of intestinal microbiota dysbiosis and T cell changes in immunosenescence, and looks for promising targets for diagnosis or intervention of sarcopenia in the future, hoping to achieve early detection, early diagnosis and early treatment of sarcopenia and prolong the life span of healthy aging.

Indexed as

gut microbiotaimmunosenescenceintestinal dysbacteriasarcopeniaT cell senescence

Identifiers

PMID40852355
PMCPMC12367800

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.