Evidence map›Paper›PMID 40852365›Full record

ArticleFrontiers in medicine2025

Development and validation of a nomogram to predict atelectasis in adult lymph node fistula tracheobronchial tuberculosis patients.

Quhua Yin, Guojian Ou, Yi Zhou, Xiaojian Wen, Heping Huang, Jie Ling, Li Luo

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Quhua YinDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Guojian OuDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Yi ZhouDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Xiaojian WenDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Heping HuangDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Jie LingDepartment of Radiology, Hunan Chest Hospital, Changsha, China.
Li LuoEndoscopy Center, Hunan Chest Hospital, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lymph node fistula tracheobronchial tuberculosis (TBTB) is a severe respiratory condition that can result in complications such as airway stenosis and atelectasis, posing significant clinical challenges, particularly in adults. Currently, no standardized assessment tools are available to predict the risk of atelectasis in these patients, highlighting the need to develop an effective predictive model to guide early clinical intervention and personalized treatment. Methods: A retrospective study was conducted involving 547 adult patients diagnosed with lymph node fistula TBTB at our hospital between January 2017 and December 2023. Diagnoses were confirmed by chest computed tomography, bronchoscopy, and combined etiological or pathological examinations. After applying the inclusion and exclusion criteria, 301 cases were included in the final analysis. Patients were randomly assigned to a development group ( Results: Among the 301 patients with lymph node fistula TBTB, the incidence of atelectasis was 60.13% (181/301). Of those, 72.93% (132/181) had right lung involvement, and 50.28% (91/181) specifically had atelectasis in the right middle lobe. Independent predictors identified by multivariable logistic regression included age, occupation as a farmer, mediastinal lymphadenopathy with ring enhancement, and right middle lobe bronchial involvement. A risk nomogram was developed using these predictors. The area under the curve (AUC) of the nomogram was 0.824 (95% CI: 0.685-0.806) in the development group and 0.857 (95% CI: 0.702-0.877) in the validation group. Calibration plots based on 500 bootstrap resamples showed good agreement between predicted and observed probabilities across both groups. DCA revealed that the model provided a net clinical benefit within threshold probability ranges of 0.2-0.9 for the development group and 0.15-0.85 for the validation group. Conclusion: The predictive model and associated nomogram developed in this study can accurately estimate the risk of atelectasis in adult patients with lymph node fistula TBTB. This tool may assist clinicians in developing individualized intervention strategies.

Indexed as

atelectasisbronchial diseaseslymph node fistulanomogramprediction modeltuberculosis

Identifiers

PMID40852365
PMCPMC12367512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.