Evidence map›Paper›PMID 40852989›Full record

ArticlemBio2025

A novel regulator of the fungal phosphate starvation response revealed by transcriptional profiling and DNA affinity purification sequencing.

Lori B Huberman, Vincent W Wu, David J Kowbel, Juna Lee, Chris Daum, Vasanth R Singan, Igor V Grigoriev, Ronan C O'Malley, N Louise Glass

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Lori B HubermanPlant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-2638-8528
Vincent W WuPlant and Microbial Biology Department, University of California, Berkeley, California, USA.ORCID 0000-0001-9973-2508
David J KowbelPlant and Microbial Biology Department, University of California, Berkeley, California, USA.ORCID 0000-0003-3985-8576
Juna LeeUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Chris DaumUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0003-3895-5892
Vasanth R SinganUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0002-9983-5707
Igor V GrigorievPlant and Microbial Biology Department, University of California, Berkeley, California, USA.ORCID 0000-0002-3136-8903
Ronan C O'MalleyUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0002-4907-0339
N Louise GlassPlant and Microbial Biology Department, University of California, Berkeley, California, USA.ORCID 0000-0002-4844-2890

Funding

POSTGRADUATE TRAINING PROGRAM IN GENETICST32GM007127 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 1985 to 2016
$7.9M
Genetic mechanisms of signal integration in the nutrient sensing networkR35GM150926 · NIGMS · CORNELL UNIVERSITY · PI Lori B Huberman · 2023 to 2026
$1.5M
Energy Biosciences InstituteJoint Genome Institute CSP 982Lawrence Berkeley National Laboratory DE-AC02-05CH11231NIGMS NIH HHS R35 GM150926NIGMS NIH HHS T32 GM007127NIH HHS 5T32GM007127-39NIH HHS R35GM150926University of California, Berkeley Foundation Fred E. Dickinson Chair of Wood Science and Technology
6 · The paper itself

Abstract

Cells must accurately sense and respond to nutrients to compete for resources and establish growth. Phosphate is a critical nutrient source necessary for signaling, energy metabolism, and synthesis of nucleic acids, phospholipids, and cellular metabolites. During phosphate limitation, fungi import phosphate from the environment and liberate phosphate from phosphate-containing molecules in the cell. In the model filamentous fungus

Indexed as

Fungal ProteinsGene Expression Regulation, FungalNeurospora crassaPhosphatesTranscription FactorsGene Expression ProfilingFungal ProteinsPhosphatesTranscription FactorsDNA affinity purification sequencingfilamentous fungiNeurosporaphosphate starvation responsetranscriptional profilingtranscription factor regulatory network

Identifiers

PMID40852989
PMCPMC12506109

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.