Evidence map›Paper›PMID 40853149›Full record

ArticleMicrobiology spectrum2025

Single-cell RNA sequencing defines developmental progression and reproductive transitions of

Aaron W Albee, Steven G Sayson, Alan Ashbaugh, Nicholas J Wolf, Aleksey Porollo, George Smulian, Melanie T Cushion

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Advances in pathogen detection ofInfectious medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron W AlbeeDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.ORCID 0009-0008-5840-1890
Steven G SaysonDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0002-7461-0704
Alan AshbaughDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Nicholas J WolfDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Aleksey PorolloCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0002-3202-5099
George SmulianDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Melanie T CushionDepartment of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0001-6621-2784

Funding

The role of sex in the life cycle and transmission of PneumocystisR01HL146266 · NHLBI · UNIVERSITY OF CINCINNATI · PI CUSHION, MELANIE T · 2019 to 2022
$1.9M
Elucidating the Sexual Cycle of HIV/AIDS-Related Pneumocystis PneumoniaR01HL176858 · NHLBI · UNIVERSITY OF CINCINNATI · PI Melanie T Cushion, Alexey Porollo · 2025 to 2026
$976k
BLRD VA I01 BX004441NHLBI NIH HHS R01 HL146266NHLBI NIH HHS R01 HL176858NIH HHS R01HL146266U.S. Department of Veterans Affairs 1I01BX004441- 01
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

Pneumocystis cariniiSingle-Cell AnalysisAnimalsBronchoalveolar Lavage FluidFungal ProteinsGene Expression ProfilingGene Expression Regulation, FungalPneumonia, PneumocystisRatsReproductionSequence Analysis, RNASpores, FungalTranscriptomeFungal Proteins10× Genomicsfungal pathogeninfectious diseaseopportunistic fungiPneumocystisPneumocystis cariniiPneumocystis pneumoniasingle-cell RNA sequencing

Identifiers

PMID40853149
PMCPMC12502742

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.