Evidence map›Paper›PMID 40853949›Full record

ArticlePloS one2025

Connection between hypoallergenic food and dyslipidemia in dogs: A nutritional myth?

Andressa Rodrigues Amaral, Thiago Henrique Annibale Vendramini, Natália Manuela Cardoso de Oliveira, Laís Oyama Cotrim Lima, Pedro Henrique Marchi, Marcio Antonio Brunetto, Júlio Cesar de Carvalho Balieiro

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andressa Rodrigues AmaralVeterinary Nutrology Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo, Brazil.
Thiago Henrique Annibale VendraminiVeterinary Nutrology Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0003-4457-8392
Natália Manuela Cardoso de OliveiraVeterinary Nutrology Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo, Brazil.
Laís Oyama Cotrim LimaVeterinary Nutrology Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo, Brazil.
Pedro Henrique MarchiPet Nutrology Research Center, School of Veterinary Medicine and Animal Science, University of Sao Paulo, University of Sao Paulo, Pirassununga, Brazil.ORCID https://orcid.org/0009-0005-0103-8785
Marcio Antonio BrunettoVeterinary Nutrology Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo, Brazil.
Júlio Cesar de Carvalho BalieiroPet Nutrology Research Center, School of Veterinary Medicine and Animal Science, University of Sao Paulo, University of Sao Paulo, Pirassununga, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited education in nutrition contributes to the spread of the "nutritionism" phenomenon, with unfounded concerns about certain diets, such as commercial hypoallergenic ones, and their supposed relationship with the development of dyslipidemia. This study aimed to evaluate the perception of veterinarians on the subject and test its veracity. For this, serum triglyceride and cholesterol data from 35 dogs were analyzed before and after consumption of a commercial hypoallergenic diet for 60 days. In addition, a survey was carried out with veterinarians to assess their beliefs about this diet. Finally, the fat content of commercial maintenance, light and other prescription diets were compared to that of 10 commercial hypoallergenic dog diets. The results showed that most veterinarians believed that hypoallergenic diets could cause dyslipidemia and has too much fat. The analysis showed that hypoallergenic diets have fat content in the range of maintenance diets and majority of prescription diets. Fat content of hypoallergenic diets was only higher than light diets and supporting diets for diabetes available in Brazil. Laboratory analysis identified no dogs with dyslipidemia development during the study. Therefore, hypoallergenic diets do not have a high fat content, but new studies should verify if, when used for prolonged periods, hypoallergenic would lead to dyslipidemia in healthy dogs or dogs with underlying diseases, as well as possible changes in the lipoprotein profile.

Indexed as

Animal FeedDietDog DiseasesDyslipidemiasFood HypersensitivityAnimalsCholesterolDogsFemaleMaleTriglyceridesCholesterolTriglycerides

Identifiers

PMID40853949
PMCPMC12377564

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.