Evidence mapPaperPMID 40854574Full record

Trial reportNephrology (Carlton, Vic.)2025

Interpretability of Home Blood Pressure Measurements in Haemodialysis A Post Hoc Analysis of a Randomised Cross-Over Study.

Vicki Sandys, Lavleen Bhat, Emer O'Hare, Amy Hudson, Conall M O'Seaghdha, Donal J Sexton

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Nephrology (Carlton, Vic.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03403491 (Pilot-scale, Randomized Study Comparing Self-monitoring of Weight and Blood Pressure Via an Electronic Health Journal), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03403491 nacompletednot on this map

Pilot-scale, Randomized Study Comparing Self-monitoring of Weight and Blood Pressure Via an Electronic Health Journal (patientMpower Platform) With Usual Care in Haemodialysis Patients

TypeinterventionalSponsorpatientMpower Ltd.Ran2018 to 2019Enrolled43ConditionsRenal DialysisArmspatientMpower application, sham application
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vicki SandysRoyal College of Surgeons in Ireland, Dublin, Ireland.ORCID https://orcid.org/0000-0002-3681-5346
Lavleen BhatRoyal College of Surgeons in Ireland, Dublin, Ireland.
Emer O'HareRoyal College of Surgeons in Ireland, Dublin, Ireland.
Amy HudsonBeaumont Hospital Dublin, Dublin, Ireland.
Conall M O'SeaghdhaRoyal College of Surgeons in Ireland, Dublin, Ireland.
Donal J SextonSt James's Hospital Dublin, Dublin, Ireland.

Funding

Enterprise Ireland, Disruptive Technologies Innovation Fund DT 2019 0086Health Research Board ARPP-P-2018-011Health Service Executive Quality Innovation Corridor programme ICT18-004 QIC
6 · The paper itself

Abstract

aimWe aimed to assess patterns of home BP in a maintenance haemodialysis cohort in line with consensus guidelines and determine the agreement with in-centre BP.

methodsA post hoc analysis of a pilot-scale, randomised two-period cross-over study comparing self-monitoring of BP over 4 weeks with usual care in 41 haemodialysis patients. Dialysis systolic BP (SBP) was compared with (i) home SBP averaged over 24 h, (ii) home SBP measurements on non-dialysis days between 6 pm-12 am and 6 am-12 pm.

resultsThirty-three participants with a mean age of 50 ± 14 years provided sufficient blood pressure data. Post-dialysis SBP moderately agreed with home SBP measurements (K = 0.65) when averaged over 2 weeks on non-dialysis days. The limits of agreement and mean bias were minimally different between 2-week averaged home SBP and post-dialysis SBP (mean bias -4.44 mmHg, 95% CI for mean difference between methods -61.63 to 52.59 mmHg), versus 24 h averaged home SBP and post-SBP (mean bias -2.32, limits of agreement -61.63 to 56.98 mmHg). Home SBP measurements were as variable [average real variability (16 ± 6)] as in-centre pre-dialysis SBP average real variability (14 ± 5) and post-SBP average real variability (13 ± 5).

conclusionThis study demonstrates the variability of BP measurement patterns if participants are not limited to measuring BP at a pre-specified frequency. Further studies are needed to assess optimal methods of standardising home BP monitoring in dialysis patients and to evaluate home BP thresholds that can be used as targets in randomised controlled trials.

trial registrationwww. CLINICALTRIALS: gov. NCT03403491.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryRenal DialysisAdultAgedCross-Over StudiesFemaleHumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsReproducibility of ResultsTime Factorsblood pressure variabilitycardiovascularERA‐EDTA guidelineshaemodialysishome BPhypertension

Identifiers

PMID40854574
PMCPMC12377942

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.