Evidence map›Paper›PMID 40854658›Full record

ArticleJournal, genetic engineering & biotechnology2025

Green synthesis of silver nanoparticles using Pyrostegia venusta extract, characterization and estimation of antioxidant, antiglycation and anti-aging activities.

Regildo Márcio Gonçalves da Silva, Pedro Augusto Pereira Rosatto, Isabelly do Nascimento Pereira, Laura Camargo Zibordi, Hugo Henrique Santos, Filipe Oliveira Granero, Célia Cristina Malaguti Figueiredo, Patrícia Soares Santiago, Carlos Augusto Prata Gaona, Nilson Nicolau-Junior and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Regildo Márcio Gonçalves da SilvaSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil; São Paulo State University (UNESP), Institute of Chemistry, Araraquara, São Paulo, Brazil. Electronic address: regildo.silva@unesp.br.
Pedro Augusto Pereira RosattoSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil; São Paulo State University (UNESP), School of Agricultural Sciences, Registro, São Paulo, Brazil.
Isabelly do Nascimento PereiraSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil.
Laura Camargo ZibordiSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil.
Hugo Henrique SantosSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil.
Filipe Oliveira GraneroSão Paulo State University (UNESP), Institute of Chemistry, Araraquara, São Paulo, Brazil.
Célia Cristina Malaguti FigueiredoSão Paulo State University (UNESP), School of Sciences, Humanities and Languages, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Assis, São Paulo, Brazil; São Paulo State University (UNESP), Institute of Chemistry, Araraquara, São Paulo, Brazil.
Patrícia Soares SantiagoSão Paulo State University (UNESP), School of Agricultural Sciences, Registro, São Paulo, Brazil.
Carlos Augusto Prata GaonaSão Paulo State University (UNESP), School of Agricultural Sciences, Registro, São Paulo, Brazil.
Nilson Nicolau-JuniorFederal University of Uberlândia (UFU), Institute of Biotechnology, Laboratory of Molecular Modeling, Uberlândia, Minas Gerais, Brazil.
Luciana Pereira SilvaSão Paulo State University (UNESP), Institute of Chemistry, Araraquara, São Paulo, Brazil; Fundação Educacional do Município de Assis (FEMA), Assis, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrostegia venusta presents phytoconstituents with biological properties including antioxidant activity. This study aimed to prepare P. venusta aqueous extract (PvAE), synthesize silver nanoparticles (AgNPs) through green synthesis using PvAE, determine their phytoconstituents, evaluate their in vitro antioxidants, antiglycation, and anti-aging activities, and analyze in silico docking of the main phenolic compounds. Phytoconstituents were identified by HPLC and determined by total polyphenols and flavonoids. AgNPs were characterized by scanning transmission electron microscopy and dynamic light scattering. Evaluation of antioxidant potential was performed by DPPH radical scavenging, FRAP, TBARS, ORAC, and oxidative hemolysis analysis. Evaluation of antiglycation activity was carried out by the determination of free amino groups, inhibition of AGEs formation, and REM assays. Anti-aging pandal was evaluated by in vitro and in silico assays. PvAE exhibited the highest total polyphenols (325.78 mg gallic acid equivalent g

Indexed as

AgingEnzyme inhibitionFlavonoidsFree radicalsMetallic nanoparticlesProtein glycation

Identifiers

PMID40854658
PMCPMC12312050

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.