ArticleBioData mining2025
Mapping the evolving trend of research on efferocytosis: a comprehensive data-mining-based study.
Article in BioData mining, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A temporal keyword co-occurrence network mining framework for detecting structural transitions in cancer biomarker research (2006-2023).Scientific reports · 2026Article
- Efferocytosis in Health and Disease.MedComm · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEfferocytosis, the process by which apoptotic cells are recognized and removed by phagocytes, plays a critical role in maintaining tissue homeostasis and modulating inflammatory responses. Over recent decades, an increasing number of studies have investigated the molecular mechanisms and clinical implications of efferocytosis. This bibliometric analysis aims to map the evolving trends, identify key contributors, and outline emerging research themes in this field.
methodsA comprehensive search was conducted in Web of Science database, to collect literature related to efferocytosis from 2006 to 2024. The dataset was analyzed using several tools such as CiteSpace and VOSviewer. Analyses included evaluation of publication trends, citation networks, keyword co-occurrence, and co-cited references. Key metrics such as the most prolific authors, top contributing countries, and major research clusters were identified to understand the field's evolution and interdisciplinary collaborations.
resultsThe final dataset comprised 1549 scholarly works, consisting of 1166 original research articles and 383 review papers. The analysis revealed a steady increase in the number of publications concerning efferocytosis, particularly in the past decade. Geographically, China and the United States emerged as dominant contributors, representing over 64.4% of total publications. Among institutions, Harvard University demonstrated the highest research output in this field. Keyword analysis demonstrated the current research focus including molecular mechanisms and signaling regulation of efferocytosis, macrophage polarization and inflammatory modulation, pathological implications and therapeutic potential of efferocytosis in diseases. Inflammation, atherosclerosis, cardiovascular disease, myocardial infarction, and COPD are diseases that has received the most attention in this field. Several research topics including nanoparticle, neuroinflammation, fibrosis, immunometabolism, exosomes, apoptotic bodies, mesenchymal stem cells, aging, microglia, reactive oxygen species, CD47, lipid metabolism, immunotherapy, mitochondria, ferroptosis, may have great potential to be hot topics in the near future. Gene-focused investigations identified TNF, MERTK, IL10, LI6, and IL1b as the most extensively studied genetic elements in efferocytosis research.
conclusionsThis bibliometric study provides a comprehensive overview of the evolving research landscape in efferocytosis. These insights not only highlight the current milestones but also serve as a valuable guide for future research and policy-making aimed at harnessing efferocytosis for therapeutic innovations.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.