ArticleThe International journal of eating disorders2025
Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery.
Article in The International journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Enhancing Postoperative Outcomes After Metabolic Bariatric Surgery: a Pilot Study of Inhibitory Control Training, Transcranial Direct Current Stimulation and Psychosocial Aftercare.Obesity surgery · 2026Trial
- Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery.The International journal of eating disorders · 2025Article
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12 authors.
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Abstract
objectiveObesity surgery (OS) results in substantial, albeit heterogeneous, long-term improvements in weight and mental health, with unclear trajectories and their associations. This study examined multivariate trajectories of weight, psychopathology, and health-related quality of life (HRQOL) after OS, and their prospective association with long-term health outcomes.
methodIn the prospective multicenter Psychosocial Registry of Obesity Surgery, N = 856 patients were classified into multivariate trajectory classes using latent class linear mixed models, based on assessments of weight, depression, eating disorder psychopathology, and HRQOL at baseline and annually 1-5 years following OS. The prognostic significance of trajectory classes for 6-year follow-up was examined. Multivariate trajectory modeling was compared with univariate weight trajectory modeling for concordance and prognostic significance.
resultsWe identified three trajectory classes of low (I, 2.8%), medium (II, 89.1%), and high (III, 8.1%) sustainability 1-5 years after OS, indicating high (I) or gradual deterioration (II) or further improvement (III) after initial improvement of indicators. The low sustainability class (I) reached nadir improvements earliest. Consistently, trajectory classes were prospectively associated with differential clinically significant improvement in weight and mental health at the 6-year follow-up. Multivariate trajectory modeling was discordant with univariate weight trajectory modeling and showed greater predictive value for health outcomes at the 6-year follow-up. DISCUSSION: Patients who achieve nadir improvements in weight and mental health early may require clinical attention to prevent long-term relapse. Monitoring changes in the first years after OS appears essential to identify patients in need of additional intervention, ideally using indicators beyond weight, such as mental health.
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