SynthesisBiogerontology2025
Blueberries for brainpower: A systematic review and meta-analysis with Bayesian post hoc analysis of RCTS exploring cognitive function in the elderly with prior cognitive decline.
Synthesis in Biogerontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Berry Consumption and Its Role in the Modulation of Obesity and Mild Cognitive Impairment.Nutrients · 2026Pooled it
- A Review ofFoods (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blueberries are anthocyanin-rich fruits widely consumed by the general population, with well-established health benefits on the endocrine and cardiovascular systems attributed to their potent anti-inflammatory properties. However, the potential impact of blueberry consumption on cognitive function in elderly individuals with prior cognitive decline, such as Alzheimer's disease and dementia, remains insufficiently explored in the literature. Therefore, we aimed to evaluate the potential effects of chronic blueberry consumption on cognitive performance in this population through various memory assessment tools. We searched PubMed, Embase, and Cochrane for randomized controlled trials (RCTs) evaluating the effect of chronic blueberry consumption on cognitive function. We pooled standard mean differences (SMD) and 95% confidence interval (CI) using a random-effects model. We identified nine eligible RCTs involving 513 patients. In elderly individuals with mild cognitive impairment (MCI) and subjective cognitive decline, blueberry intake showed a statistically significant improvement in episodic memory. (SMD = 0.34; 95% CI 0.11 to 0.57; p < 0.05). The subgroup analysis revealed that diagnostic objetivity was not a statistically significant effect modifier. Blueberry intake was also associated with improved language memory in MCI patients (SMD = 0.30; 95% CI 0.01 to 0.60; p < 0.05). No improvements were seen in processing speed (SMD = - 0.33; 95% CI - 0.85 to 0.19, p > 0.05), recognition memory (SMD = 0.14; 95% CI - 0.17 to 0.46, p > 0.05), visuospatial learning (SMD = 0.32; 95% CI - 0.16 to 0.79, p > 0.05) and working memory (SMD = 0.09; 95% CI - 0.21 to 0.39, p > 0.05). Chronic blueberry intake may improve episodic memory in the elderly with MCI and subjective cognitive decline, and also language in the elderly with MCI. These findings should be confirmed in further multicenter trials to confirm generalizability and long-term impact.
Indexed as
Identifiers
40856863What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.