ArticleCell reports2025
Nrf2 drives activation-driven expansion of CD4
Abstract read
In one paragraph
Article in Cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Crosstalk Between Nrf2 and Metabolic Pathways: Redox Regulation, Glutaminolysis, and Cellular Proliferation.Cell biochemistry and biophysics · 2026Review
- Hudi enteric-coated capsule and its active constituent polydatin suppress Th1/Th17-mediated intestinal inflammation by modulating the KEAP1-NFE2L2 signaling pathway.Precision clinical medicine · 2026Article
- Transcriptomic landscape of peripheral T cells following CAR-T cell therapy in diffuse large B cell lymphoma.Cancer immunology, immunotherapy : CII · 2026Article
- Selenium‑based nanotherapeutics promote healing of infected diabetic wounds via photothermal‑driven macrophage immunometabolic reprogramming and the NRF2/HIF‑1α axis.Journal of nanobiotechnology · 2026Article
- Protocol for intranuclear Nrf2 detection in activated mouse, human, and Jurkat T cells by spectral flow cytometry.STAR protocols · 2026Article
- Glutamine alleviates Staphylococcus aureus-induced mastitis by modulating macrophage polarisation.PLoS pathogens · 2026Article
- Food preservative tBHQ modulates Th17/TCurrent research in toxicology · 2026Article
- From metabolism to genome integrity: NRF2 as a key mediator of cancer therapy response.Frontiers in cell and developmental biology · 2026Review
- Identification of the oxidation stress-related gene signatures and functional verification of MINK1 in prostate cancer cells.PloS one · 2026Article
- Nrf2 as a Molecular Guardian of Redox Balance and Barrier Integrity in IBD.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
- Update of
Authors and funding
16 authors.
Aprajita TripathiDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Debolina DasguptaDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Michael S DahabiehDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA; Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA.
Rachel Griffard-SmithDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Anil PantDepartment of Biology, Kansas State University, Manhattan, KS, USA.
Ashlyn BugbeeDepartment of Biology, Kansas State University, Manhattan, KS, USA.
Nanda Kumar YellapuDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Emily BurtDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Ben H Y ChoiDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Abigail E EllisMass Spectrometry Core Facility, Van Andel Institute, Grand Rapids, MI, USA.
Ryan D SheldonDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA; Mass Spectrometry Core Facility, Van Andel Institute, Grand Rapids, MI, USA.
Shailendra GiriDepartment of Neurology, Henry Ford Health, Detroit, MI, USA.
Devin KoestlerDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Russell G JonesDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA; Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA.
Viveka Nand YadavDepartment of Pediatrics, Children's Mercy Research Institute (CMRI), Kansas City, MO, USA; Department of Pediatrics, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Kalyani PyaramDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA. Electronic address: kpyaram@kumc.edu.
Funding
Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0MTransgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1MUniversity of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mohammad Haeri · 2021 to 2026
$25.3MUsing Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Diane E Mahoney · 2019 to 2026
$21.5MNovel Approaches for the Control of Microbial PathogensP30GM103326 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LUTKENHAUS, JOSEPH F · 2012 to 2016
$5.3MNCI NIH HHS P30 CA168524NIA NIH HHS P30 AG072973NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM130423NIGMS NIH HHS P30 GM103326
Abstract
Upon antigenic stimulation, CD4
Indexed as
CD4-Positive T-LymphocytesGlucoseGlutamineNF-E2-Related Factor 2AnimalsCell ProliferationInterleukin-2Kelch-Like ECH-Associated Protein 1Lymphocyte ActivationMiceMice, Inbred C57BLReceptors, Antigen, T-CellSignal TransductionGlucoseGlutamineInterleukin-2Kelch-Like ECH-Associated Protein 1Nfe2l2 protein, mouseNF-E2-Related Factor 2Receptors, Antigen, T-Celladaptive immune cellsantioxidationCP: ImmunologyCP: MetabolismimmunometabolismT cell activationT cell expansion
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.