Evidence map›Paper›PMID 40858382›Full record

Observational studyBMJ open2025

Patient and physician preferences for cancer panel testing in Japan: a best-worst scaling study.

Yoshiyuki Suehara, Kazuo Hasegawa, Yoshiyuki Majima, Naoyuki Mita, Sylvaine Barbier, Nataliya Bogoeva, Shunsuke Kato

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04607889 (Measurement of Patient Views on the Attributes of Cancer Genomic Medicine in Japan), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04607889 completednot on this map

Measurement of Patient Views on the Attributes of Cancer Genomic Medicine in Japan (Patient View Study)

TypeobservationalSponsorBayerRan2020 to 2022Enrolled605ConditionsCancer Genomic ProfilingArmsSurvey
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshiyuki SueharaDepartment of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazuo HasegawaNPO Lung Cancer Patients Association One Step, Kanagawa, Japan.
Yoshiyuki MajimaRare Cancers Japan, Tokyo, Japan.
Naoyuki MitaBayer Yakuhin, Ltd, Tokyo, Japan naoyuki.mita@icloud.com.ORCID http://orcid.org/0000-0003-2698-037X
Sylvaine BarbierPutnam, Lyon, France.
Nataliya BogoevaPutnam, Sofia, Bulgaria.
Shunsuke KatoDepartment of Clinical Oncology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the relative importance of the benefits and burdens of comprehensive genomic profiling testing from the perspectives of patients and physicians in Japan.

designCross-sectional preference elicitation via a mixed method centred on best-worst scaling (BWS) case 2 (profile case), including qualitative stages to define the attributes and pilot the survey.

settingOnline surveys for patients who are members of patient advocacy groups and for physicians registered with a survey panel.

participantsA preference study was conducted among 229 patients with lung or rare cancers and 329 physicians treating lung or rare cancers. PRIMARY AND SECONDARY OUTCOME MEASURES: BWS scores indicating patient and physician preferences for comprehensive genomic profiling tests.

resultsThe best benefit of panel testing for the patients was that all samples would yield results (coefficient 5.36). They also valued that the cost of the test paid directly by the patient is ¥0 (coefficient 5.28) and that a blood sample is used (coefficient 4.87). They perceived the cost of ¥800 000, duration of the testing process (3 months) and the lack of a detailed explanation of the test as the primary disadvantages (coefficients -0.45, reference level, 0.09, respectively). The physicians highlighted the following essential attributes for panel testing: all samples will yield results, a blood sample is used and a sample collected in the past is used (coefficients 4.66, 4.17, 4.10, respectively). In their view, the most negative attribute level was that the cost of the test is ¥800 000, followed by the duration of the testing process (3 months) and the possibility that 4 in 10 tests will not yield results due to a problem with the sample (coefficients -0.32, reference level, 0.41, respectively).

conclusionsThe results of this study provide insights that will help patients and physicians improve the panel testing process. The results will also guide the further development of panel testing technologies and the optimisation of regulatory and healthcare policies. TRIAL REGISTRATION NUMBER: NCT04607889.

Indexed as

Attitude of Health PersonnelGenetic TestingLung NeoplasmsNeoplasmsPatient PreferencePhysiciansAdultAgedCross-Sectional StudiesFemaleHumansJapanMaleMiddle AgedSurveys and QuestionnairesGenomic MedicineLung NeoplasmsONCOLOGYPatientsPhysiciansRare Diseases

Identifiers

PMID40858382
PMCPMC12382511

What Socratic holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.