Evidence map›Paper›PMID 40859336›Full record

ArticleTropical medicine and health2025

Global status and trends of proteomics in obesity: a bibliometric analysis and knowledge graph study.

Xiaoying Wu, Yongming Chen, Tong Wu, Qi Pan, Lixin Guo

Abstract read
In one paragraph

Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoying Wu *Department of Endocrinology, Beijing Hospital, Peking University Fifth School of Clinical Medicine, National Center of Gerontology, Beijing, China.
Yongming Chen *Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Tong Wu *Department of Orthopedics, Peking University Third Hospital, Beijing, China.
Qi PanDepartment of Endocrinology, Beijing Hospital, Peking University Fifth School of Clinical Medicine, National Center of Gerontology, Beijing, China. panqi621@126.com.
Lixin GuoDepartment of Endocrinology, Beijing Hospital, Peking University Fifth School of Clinical Medicine, National Center of Gerontology, Beijing, China. glxwork@163.com.

Funding

Beijing Natural Science Foundation 7244403Fundamental Research Funds for the Central Universities, Capital's Funds for Health Improvement and Research 2022-1-4051National High Level Hospital Clinical Research Funding BJ-2022-120National High Level Hospital Clinical Research Funding BJ-2022-193National High Level Hospital Clinical Research Funding BJ-2023-104National Key Research and Development Program of China 2022YFB3203700the National Natural Science Foundation of China 82170848the National Natural Science Foundation of China 82370835
6 · The paper itself

Abstract

aimsProteomics plays an essential role in uncovering the molecular mechanisms of obesity. This study aimed to map global research trends, identify major contributors, and examine evolving themes in this field over the past two decades.

methodsA bibliometric analysis was performed using the Web of Science Core Collection (WoSCC) from 1999 to February 2025. Only English-language original articles and reviews were included. CiteSpace and VOSviewer were used to analyze publication volume, collaboration networks, core journals, citation patterns, and keyword co-occurrence.

resultsA total of 1688 publications were analyzed. Research output increased steadily and peaked in 2022. The United States led in publication count and citations, followed by China and Germany. Keyword analysis revealed a clear thematic shift: early studies focused on adipose biology and hormonal regulation, while more recent work highlights topics such as gut microbiota, lipid metabolism, type 2 diabetes, and PCOS. These shifts reflect an increased focus on systemic mechanisms and a stronger link to clinical needs such as diagnosis and personalized treatment.

conclusionProteomics research in obesity has grown in both scale and complexity, with expanding global collaboration and evolving scientific priorities. This study provides a comprehensive overview of the field's development and offers direction for future translational and interdisciplinary efforts.

Indexed as

BibliometricsCiteSpaceObesityProteomicsVOS viewers

Identifiers

PMID40859336
PMCPMC12379555

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.