Evidence map›Paper›PMID 40860138›Full record

ArticleTheranostics2025

Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia.

Nishat I Tabassum, Sharmelee Selvaraji, Yibo Fan, Vernise Jt Lim, Xiangru Cheng, Xiangyuan Peng, Aayushi Arora, Vismitha Rajeev, Julian Ratcliffe, Chad J Johnson and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Nishat I TabassumDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Sharmelee SelvarajiResearch Laboratory of Electronics, Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Yibo FanDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Vernise Jt LimDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Xiangru ChengDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Xiangyuan PengDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Aayushi AroraDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Vismitha RajeevMemory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Julian RatcliffeBioimaging Platform, La Trobe University, Bundoora, VIC, Australia.
Chad J JohnsonBioimaging Platform, La Trobe University, Bundoora, VIC, Australia.
Keshava K DattaLa Trobe University-Proteomics and Metabolomics Platform (LTU-PMP), La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia.
Rohan LoweLa Trobe University-Proteomics and Metabolomics Platform (LTU-PMP), La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia.
Mansour EbrahimiDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Quynh Nhu DinhDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
T Michael De SilvaDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Christopher G SobeyDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.
Peiyan WongSignature Research Programme in Neuroscience & Behavioural Disorders, Duke-NUS Medical School, Singapore.
Eddie Feng-Ju WengNeuroscience and Brain Disease Centre, China Medical University, Taichung, Taiwan.
Dong-Gyu JoSchool of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Christopher P ChenMemory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mitchell K P LaiMemory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Thiruma V ArumugamDepartment of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainCognitive DysfunctionDementia, VascularFastingProteomeSynapsesAnimalsCarotid StenosisDisease Models, AnimalHippocampusIntermittent FastingMaleMiceMice, Inbred C57BLProteomecognitive impairmentintermittent fastingneuronal deathsynaptic lossvascular dementia

Identifiers

PMID40860138
PMCPMC12374579

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.