Evidence map›Paper›PMID 40860162›Full record

ArticleTheranostics2025

Single-cell RNA sequencing reveals that myeloid S100A8/A9 is a novel regulator of the transition from adaptive hypertrophy to heart failure after pressure overload.

Wei-Jia Yu, Wen-Xi Jiang, Shu-Jing Liu, Hui-Hua Li, Qiu-Yue Lin

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Xanthatin Attenuates Angiotensin II-Induced Cardiac Hypertrophy by Targeting CREB5.Journal of cardiovascular translational research · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei-Jia YuInstitute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Wen-Xi JiangInstitute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Shu-Jing LiuInstitute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Hui-Hua LiInstitute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Qiu-Yue LinInstitute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calgranulin ACalgranulin BCardiomegalyHeart FailureMyeloid CellsAnimalsDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLMice, KnockoutNeutrophilsSequence Analysis, RNASingle-Cell AnalysisCalgranulin ACalgranulin BS100a8 protein, mouseS100A9 protein, mousecardiac hypertrophyheart failureinflammationmacrophagesneutrophilsS100A8/A9

Identifiers

PMID40860162
PMCPMC12374730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.