Evidence map›Paper›PMID 40860189›Full record

ArticleInternational journal of biological sciences2025

Ferroptosis-Resistant Adipocytes Drive Keloid Pathogenesis via GPX4-Mediated Adipocyte-Mesenchymal Transition and Iron-Cystine Metabolic Communication.

Xiangguang Shi, Xueyi Xia, Yang Xiao, Huizhen Shu, Zhuoya Xu, Mengguo Liu, Chenyi Shi, Ying Zhang, Yining Wei, Yiyi Gong and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Xiangguang ShiDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Xueyi XiaState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Yang XiaoState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Huizhen ShuState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Zhuoya XuState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Mengguo LiuDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Chenyi ShiState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Ying ZhangDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Yining WeiDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Yiyi GongDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Wei WangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Yahui ChenState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of life science and Human Phenome Institute, Fudan University, Shanghai, China.
Jianlan LiuDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Jia HuangDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Mengkun ShiDepartment of Thoracic Surgery, Huashan Hospital & Cancer Metastasis Institute, Fudan University, Shanghai, China.
Jiucun WangDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.
Wenyu WuDepartment of Dermatology, Huashan Hospital, Deptartment of Allergy and immunology, Huashan Hospital, and Research Center of Allergy and Diseases, Shanghai Institute of Dermatology, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdipocytesFerroptosisIronKeloidPhospholipid Hydroperoxide Glutathione PeroxidaseAnimalsDeferoxamineFibroblastsHumansMaleMiceReactive Oxygen SpeciesSignal TransductionTransforming Growth Factor betaDeferoxamineIronPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesTransforming Growth Factor betaAdipocyte-Mesenchymal Transitionferroptosis resistanceGPX4interferon suppression.iron overloadKeloid

Identifiers

PMID40860189
PMCPMC12374836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.