Evidence map›Paper›PMID 40860670›Full record

ArticlePeerJ2025

Prognostic role and functional impact of cadherin genes in non-small cell lung cancer tumorigenesis: mechanistic insights from

Quanzhong Yang, Nan Feng, Feifei Shen, Lin Bai, Rihui Li, Shuang Li, Weikai Zhang

Abstract read
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quanzhong YangDepartment of Medical Laboratory, Luoyang Polytechnic, Luoyang, China.
Nan FengInterventional Operating Room, The First Affliated Hospital of Xinxiang Medical University, Xinxiang, China.
Feifei ShenDepartment of Medical Laboratory, Luoyang Polytechnic, Luoyang, China.
Lin BaiDepartment of Medical Laboratory, Luoyang Polytechnic, Luoyang, China.
Rihui LiSchool of Basic Medicine, Sanquan College of Xinxiang Medical University, Xinxiang, China.
Shuang LiDepartment of Medical Laboratory, Luoyang Polytechnic, Luoyang, China.
Weikai ZhangDepartment of Medical Laboratory, Luoyang Polytechnic, Luoyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality worldwide, with poor prognosis and limited treatment options for advanced stages. Dysregulation of cadherin expression has been implicated in various cancers, but their exact roles and diagnostic potential of these genes in NSCLC remain unclear. The aim of this study is to investigate the diagnostic and prognostic significance of cadherin family genes (CDH1, CDH2, and CDH3) in NSCLC. This study follows an experimental design, involving both

Indexed as

CadherinsCarcinogenesisCarcinoma, Non-Small-Cell LungLung NeoplasmsAntigens, CDBiomarkers, TumorCell Line, TumorComputer SimulationGene Expression Regulation, NeoplasticHumansMicroRNAsPrognosisAntigens, CDBiomarkers, TumorCadherinsCDH1 protein, humanCDH2 protein, humanCDH3 protein, humanMicroRNAsCadherin genesmiRNAsmRNAsNSCLCTherapeutic target

Identifiers

PMID40860670
PMCPMC12372785

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.