Evidence map›Paper›PMID 40860938›Full record

ReviewJournal of inflammation research2025

Pharmacological Insights and Therapeutic Applications of Leonurus in Neurological Disorders.

Yuting Wang, Xiaxue Wu, Ruofei Wu, Xiaona Sun, Yue Kang, Yue Yu

Abstract readReview
In one paragraph

Review in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Frontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuting WangSchool of Pharmacy & Fujian Center for New Drug Safety Evaluation, Fujian Medical University, Minhou County, Fuzhou, 350122, People's Republic of China.
Xiaxue WuSchool of Pharmacy & Fujian Center for New Drug Safety Evaluation, Fujian Medical University, Minhou County, Fuzhou, 350122, People's Republic of China.
Ruofei WuSchool of Pharmacy & Fujian Center for New Drug Safety Evaluation, Fujian Medical University, Minhou County, Fuzhou, 350122, People's Republic of China.
Xiaona SunSchool of Pharmacy & Fujian Center for New Drug Safety Evaluation, Fujian Medical University, Minhou County, Fuzhou, 350122, People's Republic of China.
Yue KangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, People's Republic of China.
Yue YuSchool of Pharmacy & Fujian Center for New Drug Safety Evaluation, Fujian Medical University, Minhou County, Fuzhou, 350122, People's Republic of China.ORCID 0000-0001-7905-6733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leonurus has a long history of use in traditional Chinese medicine, particularly for its therapeutic effects in gynecological disorders and its ability to promote blood circulation. Leonurus contains a variety of bioactive compounds, including alkaloids, flavonoids, and terpenoids, which demonstrate significant pharmacological activities, such as antioxidant, anti-inflammatory, and neuroprotective effects. Additionally, combining Leonurus with conventional pharmaceutical treatments may produce synergistic effects, enhancing therapeutic outcomes. This review provides a comprehensive overview of the classification, distribution, traditional uses, and recent pharmacological advancements of Leonurus, with a particular focus on its potential applications in the treatment of brain diseases. It aims to deepen understanding of Leonurus's therapeutic potential in treating neurological conditions.

Indexed as

active componentsclinical applicationsneuroprotectiontraditional Chinese medicine

Identifiers

PMID40860938
PMCPMC12377391

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.